Discovery of Indoline-2-carboxamide Derivatives as a New Class of Brain-Penetrant Inhibitors of Trypanosoma brucei.
about
Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents.Repurposing strategies for tropical disease drug discovery.Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery.Enantioselective radical process for synthesis of chiral indolines by metalloradical alkylation of diverse C(sp3)-H bonds.Novel lead compounds in pre-clinical development against African sleeping sickness
P2860
Discovery of Indoline-2-carboxamide Derivatives as a New Class of Brain-Penetrant Inhibitors of Trypanosoma brucei.
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
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2015年论文
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name
Discovery of Indoline-2-carbox ...... ibitors of Trypanosoma brucei.
@ast
Discovery of Indoline-2-carbox ...... ibitors of Trypanosoma brucei.
@en
type
label
Discovery of Indoline-2-carbox ...... ibitors of Trypanosoma brucei.
@ast
Discovery of Indoline-2-carbox ...... ibitors of Trypanosoma brucei.
@en
prefLabel
Discovery of Indoline-2-carbox ...... ibitors of Trypanosoma brucei.
@ast
Discovery of Indoline-2-carbox ...... ibitors of Trypanosoma brucei.
@en
P2093
P2860
P50
P1476
Discovery of Indoline-2-carbox ...... ibitors of Trypanosoma brucei.
@en
P2093
Frederick R J Simeons
Iain T Collie
Irene Hallyburton
Julie A Frearson
Kevin D Read
Laste Stojanovski
Laura A T Cleghorn
Lorna Campbell
Paul G Wyatt
Robert Kime
P2860
P304
P356
10.1021/ACS.JMEDCHEM.5B00596
P407
P577
2015-09-29T00:00:00Z