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Quantitative study of insulin secretion and clearance in normal and obese subjects

Quantitative study of insulin secretion and clearance in normal and obese subjects

http://www.wikidata.org/entity/Q35809498

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Insulin delivery methods: Past, present and future Central nervous system mechanisms linking the consumption of palatable high-fat diets to the defense of greater adiposity Female reproduction and type 1 diabetes: from mechanisms to clinical findings Changes in beta cell function occur in prediabetes and early disease in the Lepr (db) mouse model of diabetes.Undernutrition during suckling in rats elevates plasma adiponectin and its receptor in skeletal muscle regardless of diet composition: a protective effect?Urine C-peptide creatinine ratio can be used to assess insulin resistance and insulin production in people without diabetes: an observational study Clinical results of an automated artificial pancreas using technosphere inhaled insulin to mimic first-phase insulin secretion.PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance Obesity and type 2 diabetes: what can be unified and what needs to be individualized?The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance Is dynamic autocrine insulin signaling possible? A mathematical model predicts picomolar concentrations of extracellular monomeric insulin within human pancreatic islets.Protein profiling of pancreatic islets.Developmental programming: impact of prenatal testosterone excess and postnatal weight gain on insulin sensitivity index and transfer of traits to offspring of overweight females A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway C-peptide microheterogeneity in type 2 diabetes populations.Leptin/Adiponectin Ratios Using Either Total Or High-Molecular-Weight Adiponectin as Biomarkers of Systemic Insulin Sensitivity in Normoglycemic Women Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male mice Central effects of estradiol in the regulation of food intake, body weight, and adiposity.Interactions between insulin resistance and insulin secretion in the development of glucose intolerance.Lack of control by glucose of ultradian insulin secretory oscillations in impaired glucose tolerance and in non-insulin-dependent diabetes mellitus Fatty acids in the portal vein of the rat regulate hepatic insulin clearance Mechanism of compensatory hyperinsulinemia in normoglycemic insulin-resistant spontaneously hypertensive rats. Augmented enzymatic activity of glucokinase in beta-cells The role of hypothalamic estrogen receptors in metabolic regulation.Obesity and the development of type 2 diabetes: the effects of fatty tissue inflammation.Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.Anti-aging effects of caloric restriction: Involvement of neuroendocrine adaptation by peripheral signaling.Hypoglycemia: A Possible Link between Insulin Resistance, Metabolic Dyslipidemia, and Heart and Kidney Disease (the Cardiorenal Syndrome).Dynamics of insulin secretion and the clinical implications for obesity and diabetes Comparison of the physiological relevance of systemic vs. portal insulin delivery to evaluate whole body glucose flux during an insulin clamp β cell death and dysfunction during type 1 diabetes development in at-risk individuals.Glucose homeostasis during short-term and prolonged exposure to high altitudes.Endurance training inhibits insulin clearance and IDE expression in Swiss mice.Insulin clearance in obesity.β-Cell Sensitivity to GLP-1 in Healthy Humans Is Variable and Proportional to Insulin Sensitivity.Insulin clearance is different in men and women.Predicting diabetes using measures of β-cell function.Calorie Restriction and Matched Weight Loss From Exercise: Independent and Additive Effects on Glucoregulation and the Incretin System in Overweight Women and Men Gut hormones in the control of appetite.Glucose Homeostatic Law: Insulin Clearance Predicts the Progression of Glucose Intolerance in Humans.Racial/Ethnic Differences in Insulin Resistance and Beta Cell Function: Relationship to Racial Disparities in Type 2 Diabetes among African Americans versus Caucasians.

P2860

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P2860

Quantitative study of insulin secretion and clearance in normal and obese subjects

http://www.wikidata.org/entity/Q35809498

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1988 nî lūn-bûn

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1988年の論文

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1988年論文

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1988年論文

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1988年論文

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1988年論文

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1988年論文

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1988年论文

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1988年论文

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1988年论文

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name

Quantitative study of insulin secretion and clearance in normal and obese subjects

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Quantitative study of insulin secretion and clearance in normal and obese subjects

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Quantitative study of insulin secretion and clearance in normal and obese subjects

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Quantitative study of insulin secretion and clearance in normal and obese subjects

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Quantitative study of insulin secretion and clearance in normal and obese subjects

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Quantitative study of insulin secretion and clearance in normal and obese subjects

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Journal of Clinical Investigation

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Quantitative study of insulin secretion and clearance in normal and obese subjects

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B D Given

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B H Frank

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E Van Cauter

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P2860

Differential effects of oral, peripheral intravenous, and intraportal glucose on hepatic glucose uptake and insulin and glucagon extraction in conscious dogs.

Effect of intraduodenal glucose administration on hepatic extraction of insulin in the anesthetized dog

Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type I diabetic patients.

Splanchnic insulin metabolism in obesity. Influence of body fat distribution.

C-peptide as a measure of the secretion and hepatic extraction of insulin. Pitfalls and limitations.

C-Peptide and insulin secretion in Pima Indians and Caucasians: constant fractional hepatic extraction over a wide range of insulin concentrations and in obesity.

The limitations to and valid use of C-peptide as a marker of the secretion of insulin.

Measurement using tracers of steady-state turnover and metabolic clearance of insulin in dogs.

Characterization of seven C-peptide antisera.

A comparative study on the metabolism of human insulin and porcine proinsulin in man.

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