Roles of fkbN in positive regulation and tcs7 in negative regulation of FK506 biosynthesis in Streptomyces sp. strain KCTC 11604BP
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Phage p1-derived artificial chromosomes facilitate heterologous expression of the FK506 gene clusterdRNA-seq transcriptional profiling of the FK506 biosynthetic gene cluster in Streptomyces tsukubaensis NRRL18488 and general analysis of the transcriptomeTaxonomy and chemically semi-defined media for the analysis of the tacrolimus producer 'Streptomyces tsukubaensis'.Improved FK506 production by the precursors and product-tolerant mutant of Streptomyces tsukubaensis based on genome shuffling and dynamic fed-batch strategies.FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensisRoles of the crotonyl-CoA carboxylase/reductase homologues in acetate assimilation and biosynthesis of immunosuppressant FK506 in Streptomyces tsukubaensis.Significance of the natural occurrence of L- versus D-pipecolic acid: a review.Trends in the biosynthesis and production of the immunosuppressant tacrolimus (FK506).The biosynthetic pathway of FK506 and its engineering: from past achievements to future prospects.Improvement of FK506 production by synthetic biology approaches.Mutational biosynthesis of tacrolimus analogues by fkbO deletion mutant of Streptomyces sp. KCTC 11604BP.Combining metabolomics and network analysis to improve tacrolimus production in Streptomyces tsukubaensis using different exogenous feedings.Engineering of the LysR family transcriptional regulator FkbR1 and its target gene to improve ascomycin production.FkbN and Tcs7 are pathway-specific regulators of the FK506 biosynthetic gene cluster in Streptomyces tsukubaensis L19.Target genes of the Streptomyces tsukubaensis FkbN regulator include most of the tacrolimus biosynthesis genes, a phosphopantetheinyl transferase and other PKS genes.Unraveling Nutritional Regulation of Tacrolimus Biosynthesis in Streptomyces tsukubaensis through omic Approaches.Regulation of antibiotic biosynthesis in actinomycetes: Perspectives and challenges
P2860
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P2860
Roles of fkbN in positive regulation and tcs7 in negative regulation of FK506 biosynthesis in Streptomyces sp. strain KCTC 11604BP
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Roles of fkbN in positive regu ...... omyces sp. strain KCTC 11604BP
@ast
Roles of fkbN in positive regu ...... omyces sp. strain KCTC 11604BP
@en
type
label
Roles of fkbN in positive regu ...... omyces sp. strain KCTC 11604BP
@ast
Roles of fkbN in positive regu ...... omyces sp. strain KCTC 11604BP
@en
prefLabel
Roles of fkbN in positive regu ...... omyces sp. strain KCTC 11604BP
@ast
Roles of fkbN in positive regu ...... omyces sp. strain KCTC 11604BP
@en
P2093
P2860
P356
P1476
Roles of fkbN in positive regu ...... omyces sp. strain KCTC 11604BP
@en
P2093
Joo-Won Suh
SangJoon Mo
Sung-Kwon Lee
Yeo Joon Yoon
Yeon Hee Ban
Young Ji Yoo
P2860
P304
P356
10.1128/AEM.06766-11
P407
P577
2012-01-20T00:00:00Z