Glutathione metabolism during aging and in Alzheimer disease.
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Knockdown of glutamate-cysteine ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neuronsRegulation of glutathione synthesisThe Therapeutic Potential of Rosemary (Rosmarinus officinalis) Diterpenes for Alzheimer's DiseaseGlutathione: new roles in redox signaling for an old antioxidantMetabolomics reveals a role for the chromatin-binding protein HMGN5 in glutathione metabolismHypothesis: a unifying mechanism for nutrition and chemicals as lifelong modulators of DNA hypomethylation.The effects of dietary restriction on oxidative stress in rodents.Osteocyte apoptosis and control of bone resorption following ovariectomy in miceConsequences of age on ischemic wound healing in rats: altered antioxidant activity and delayed wound closure.Effect of glutathione redox state on Leydig cell susceptibility to acute oxidative stress.Antioxidant therapy in Alzheimer's disease: theory and practice.The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.Accelerating neuronal aging in in vitro model brain disorders: a focus on reactive oxygen speciesGlutathione-related antioxidant defense system in elderly patients treated for hypertension.Impaired adaptive cellular responses to oxidative stress and the pathogenesis of Alzheimer's diseaseLipoic acid significantly restores, in rats, the age-related decline in vasomotion.Augmented cystine-glutamate exchange by pituitary adenylate cyclase-activating polypeptide signaling via the VPAC1 receptor.Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementationA simple assay for glutathione in whole bloodComparison between the effects of aging and hyperoxia on glutathione redox state and protein mixed disulfides in Drosophila melanogasterMetabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities.Mitochondrial- and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers.Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: an association study with mechanistic implications.A nutrient-dense, high-fiber, fruit-based supplement bar increases HDL cholesterol, particularly large HDL, lowers homocysteine, and raises glutathione in a 2-wk trial.Transforming growth factor β suppresses glutamate-cysteine ligase gene expression and induces oxidative stress in a lung fibrosis modelOxidative stress response and Nrf2 signaling in aging.p53 orchestrates the PGC-1α-mediated antioxidant response upon mild redox and metabolic imbalance.Naturally occurring variation in the Glutathione-S-Transferase 4 gene determines neurodegeneration after traumatic brain injury.Effect of glutathione depletion on Leydig cell steroidogenesis in young and old brown Norway rats.Restoration of glyoxalase enzyme activity precludes cognitive dysfunction in a mouse model of Alzheimer's disease.Therapeutic potential and anti-amyloidosis mechanisms of tert-butylhydroquinone for Alzheimer's disease.LPS alters pattern of sickness behavior but does not affect glutathione level in aged male rats.Glutathione dysregulation and the etiology and progression of human diseases.Transcriptional regulation of rat gamma-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element.Mechanisms of beta-N-methylamino-L-alanine induced neurotoxicity.The roles of neutral sphingomyelinases in neurological pathologies.Electrochemical determination of glutathione: a review.Age-related changes in cellular protection, purification, and inflammation-related gene expression: role of dietary phytonutrients.Tackling the aging process with bio-molecules: a possible role for caloric restriction, food-derived nutrients, vitamins, amino acids, peptides, and minerals.Beta-amyloidolysis and glutathione in Alzheimer's disease.
P2860
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P2860
Glutathione metabolism during aging and in Alzheimer disease.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Glutathione metabolism during aging and in Alzheimer disease.
@ast
Glutathione metabolism during aging and in Alzheimer disease.
@en
type
label
Glutathione metabolism during aging and in Alzheimer disease.
@ast
Glutathione metabolism during aging and in Alzheimer disease.
@en
prefLabel
Glutathione metabolism during aging and in Alzheimer disease.
@ast
Glutathione metabolism during aging and in Alzheimer disease.
@en
P2093
P356
P1476
Glutathione metabolism during aging and in Alzheimer disease.
@en
P2093
Honglei Liu
Rui-Ming Liu
Swapna Shenvi
Tory M Hagen
P304
P356
10.1196/ANNALS.1297.059
P407
P577
2004-06-01T00:00:00Z