PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2(+) breast cancer cells by inducing Bim.
about
Mechanisms Behind the Resistance to Trastuzumab in HER2-Amplified Breast Cancer and Strategies to Overcome ItRegulation of Bim in Health and DiseaseIdentification of potential new treatment response markers and therapeutic targets using a Gaussian process-based method in lapatinib insensitive breast cancer models.Synergistic effects of various Her inhibitors in combination with IGF-1R, C-MET and Src targeting agents in breast cancer cell linesProtein tyrosine kinase 6 promotes ERBB2-induced mammary gland tumorigenesis in the mouse.Efficacy and mechanism of action of the tyrosine kinase inhibitors gefitinib, lapatinib and neratinib in the treatment of HER2-positive breast cancer: preclinical and clinical evidenceCombination of siRNA-directed gene silencing with epigallocatechin-3-gallate (EGCG) reverses drug resistance in human breast cancer cellsThe expression and prognostic value of protein tyrosine kinase 6 in early-stage cervical squamous cell cancer.Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells.PTK6 regulates growth and survival of endocrine therapy-resistant ER+ breast cancer cells.MiR-1268b confers chemosensitivity in breast cancer by targeting ERBB2-mediated PI3K-AKT pathway.Overexpression of PTK6 predicts poor prognosis in bladder cancer patients.Gefitinib or lapatinib with foretinib synergistically induce a cytotoxic effect in melanoma cell lines.Small molecule inhibitors reveal PTK6 kinase is not an oncogenic driver in breast cancers.
P2860
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P2860
PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2(+) breast cancer cells by inducing Bim.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
PTK6 inhibition promotes apopt ...... cancer cells by inducing Bim.
@ast
PTK6 inhibition promotes apopt ...... cancer cells by inducing Bim.
@en
type
label
PTK6 inhibition promotes apopt ...... cancer cells by inducing Bim.
@ast
PTK6 inhibition promotes apopt ...... cancer cells by inducing Bim.
@en
prefLabel
PTK6 inhibition promotes apopt ...... cancer cells by inducing Bim.
@ast
PTK6 inhibition promotes apopt ...... cancer cells by inducing Bim.
@en
P2093
P2860
P1476
PTK6 inhibition promotes apopt ...... cancer cells by inducing Bim.
@en
P2093
Gwyneth Halstead-Nussloch
Hanna Y Irie
Igor Katsyv
Koichi Ito
Sun Hee Park
William Olcott
P2860
P2888
P356
10.1186/S13058-015-0594-Z
P577
2015-06-19T00:00:00Z
P5875
P6179
1053428048