Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B12) absorption in vivo.
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Imerslund-Gräsbeck syndrome (selective vitamin B(12) malabsorption with proteinuria)Targeted disruption of cubilin reveals essential developmental roles in the structure and function of endoderm and in somite formationAMN directs endocytosis of the intrinsic factor-vitamin B(12) receptor cubam by engaging ARH or Dab2Inherited metabolic disease in companion animals: searching for nature's mistakesFrom bowel to kidneys: the role of cubilin in physiology and diseaseDab2, megalin, cubilin and amnionless receptor complex might mediate intestinal endocytosis in the suckling ratMan's best friend becomes biology's best in show: genome analyses in the domestic dogA frameshift mutation in the cubilin gene (CUBN) in Border Collies with Imerslund-Gräsbeck syndrome (selective cobalamin malabsorption).Inborn errors of cobalamin absorption and metabolism.Hepatic fungal infection in a young beagle with unrecognised hereditary cobalamin deficiency (Imerslund-Gräsbeck syndrome).The effect of progressive glomerular disease on megalin-mediated endocytosis in the kidneyCubilin is essential for albumin reabsorption in the renal proximal tubule.The kidney in vitamin B12 and folate homeostasis: characterization of receptors for tubular uptake of vitamins and carrier proteins.Proximal tubule endocytic apparatus as the specific renal uptake mechanism for vitamin D-binding protein/25-(OH)D3 complex.Cubilin expression is monoallelic and epigenetically augmented via PPARs.Detailed investigations of proximal tubular function in Imerslund-Gräsbeck syndrome.Juvenile selective vitamin B₁₂ malabsorption: 50 years after its description-10 years of genetic testingLuminal expression of cubilin is impaired in Imerslund-Grasbeck syndrome with compound AMN mutations in intron 3 and exon 7.Klf15 Is Critical for the Development and Differentiation of Drosophila NephrocytesFailure to thrive and life-threatening complications due to inherited selective cobalamin malabsorption effectively managed in a juvenile Australian shepherd dog.Increases in plasma holotranscobalamin can be used to assess vitamin B-12 absorption in individuals with low plasma vitamin B-12Inherited cobalamin malabsorption. Mutations in three genes reveal functional and ethnic patterns.Acquired and inherited disorders of cobalamin and folate in children.Cubilin and amnionless mediate protein reabsorption in Drosophila nephrocytes.Degenerative liver disease in young Beagles with hereditary cobalamin malabsorption because of a mutation in the cubilin geneAn exon 53 frameshift mutation in CUBN abrogates cubam function and causes Imerslund-Gräsbeck syndrome in dogsSelective intestinal cobalamin malabsorption with proteinuria (Imerslund-Gräsbeck syndrome) in juvenile Beagles.Age-related lysosomal dysfunction: an unrecognized roadblock for cobalamin trafficking?Receptor-Mediated Endocytosis in the Proximal Tubule.The endocytic receptor megalin and its associated proteins in proximal tubule epithelial cells.Apical sorting of ADAMTS13 in vascular endothelial cells and Madin-Darby canine kidney cells depends on the CUB domains and their association with lipid rafts.Lack of megalin expression in adult human terminal ileum suggests megalin-independent cubilin/amnionless activity during vitamin B12 absorptionSystemic Scedosporium prolificans infection in an 11-month-old Border collie with cobalamin deficiency secondary to selective cobalamin malabsorption (canine Imerslund-Gräsbeck syndrome).Canine breed predispositions for marked hypocobalaminaemia or decreased folate concentration assessed by a laboratory survey.Expression of cubilin in mouse testes and Leydig cells.Amnionless-mediated glycosylation is crucial for cell surface targeting of cubilin in renal and intestinal cells.Vitamin B12 deficiency and impaired expression of amnionless during aging.Expression of amnionless in mouse testes and Leydig cells.A frameshift mutation in the cubilin gene (CUBN) in Beagles with Imerslund-Gräsbeck syndrome (selective cobalamin malabsorption).Prospective long-term evaluation of parenteral hydroxocobalamin supplementation in juvenile beagles with selective intestinal cobalamin malabsorption (Imerslund-Gräsbeck syndrome).
P2860
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P2860
Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B12) absorption in vivo.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Amnionless function is require ...... tamin B12) absorption in vivo.
@ast
Amnionless function is require ...... tamin B12) absorption in vivo.
@en
type
label
Amnionless function is require ...... tamin B12) absorption in vivo.
@ast
Amnionless function is require ...... tamin B12) absorption in vivo.
@en
prefLabel
Amnionless function is require ...... tamin B12) absorption in vivo.
@ast
Amnionless function is require ...... tamin B12) absorption in vivo.
@en
P2093
P2860
P50
P1433
P1476
Amnionless function is require ...... tamin B12) absorption in vivo.
@en
P2093
Adam Kilkenney
Alejandro A Schäffer
Brittany Gregory
Erik I Christensen
Ewen F Kirkness
Henrik Vorum
John C Fyfe
Mette Madsen
Qianchuan He
Stephan M Tanner
P2860
P304
P356
10.1182/BLOOD-2005-03-1197
P407
P577
2005-04-21T00:00:00Z