SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion

SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion

Item
http://www.wikidata.org/entity/Q35849382
Modulation of pancreatic exocrine and endocrine secretionGlucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic SuccessesRegulation of translesion DNA synthesis: Posttranslational modification of lysine residues in key proteinsDeSUMOylation Controls Insulin Exocytosis in Response to Metabolic Signals.SUMOylation protects against IL-1β-induced apoptosis in INS-1 832/13 cells and human islets.AMPK is involved in the regulation of incretin receptors expression in pancreatic islets under a low glucose concentration.Chronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic β-cells via protein kinase APancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational AnalysisIsocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cellsAutophagy deficiency in β cells blunts incretin-induced suppression of glucagon release from α cellsSenp2 expression was induced by chronic glucose stimulation in INS1 cells, and it was required for the associated induction of Ccnd1 and Mafa.Both conditional ablation and overexpression of E2 SUMO-conjugating enzyme (UBC9) in mouse pancreatic beta cells result in impaired beta cell function.A post-translational balancing act: the good and the bad of SUMOylation in pancreatic islets.
P2860

SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion

Item
http://www.wikidata.org/entity/Q35849382
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion
@ast
SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion
@en
type
label
SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion
@ast
SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion
@en
prefLabel
SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion
@ast
SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion
@en
P2093
P2860
P304
P31
P356
10.1152/AJPENDO.00486.2011
P433
P478
P577
P5875
P698
P932