Silencing of parathyroid hormone (PTH) receptor 1 in T cells blunts the bone anabolic activity of PTH - Test2 - elhamkhani - TriplyDB

Silencing of parathyroid hormone (PTH) receptor 1 in T cells blunts the bone anabolic activity of PTH

Silencing of parathyroid hormone (PTH) receptor 1 in T cells blunts the bone anabolic activity of PTH

http://www.wikidata.org/entity/Q35849800

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The Role of IL-17 and TH17 Cells in the Bone Catabolic Activity of PTH Parathyroid hormone: anabolic and catabolic actions on the skeleton Osteoclasts: more than 'bone eaters'.T-cells and B-cells in osteoporosis The sclerostin-independent bone anabolic activity of intermittent PTH treatment is mediated by T-cell-produced Wnt10b Cyclooxygenase-2 suppresses the anabolic response to PTH infusion in mice.T cell-expressed CD40L potentiates the bone anabolic activity of intermittent PTH treatment.Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis.IL-17A Is Increased in Humans with Primary Hyperparathyroidism and Mediates PTH-Induced Bone Loss in Mice PTH expands short-term murine hemopoietic stem cells through T cells Nmp4/CIZ suppresses the parathyroid hormone anabolic window by restricting mesenchymal stem cell and osteoprogenitor frequency T cells, osteoblasts, and osteocytes: interacting lineages key for the bone anabolic and catabolic activities of parathyroid hormone.Effect of zoledronate on the responses of osteocytes to acute parathyroid hormone.Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency.The Interplay between the bone and the immune system Ovariectomy expands murine short-term hemopoietic stem cell function through T cell expressed CD40L and Wnt10B.Role of T cells in the modulation of PTH action: physiological and clinical significance The Role of Inflammatory Cytokines, the RANKL/OPG Axis, and the Immunoskeletal Interface in Physiological Bone Turnover and Osteoporosis.Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit Parathyroid hormone 1-34 and skeletal anabolic action: The use of parathyroid hormone in bone formation.Cellular complexity of the bone marrow hematopoietic stem cell niche.CTLA-4Ig-induced T cell anergy promotes Wnt-10b production and bone formation in a mouse model.Signaling pathways affecting skeletal health.Cells of the immune system orchestrate changes in bone cell function.Osteoimmunology and its implications for transplantation.Immune cells and bone: coupling goes both ways.Physiological Bone Remodeling: Systemic Regulation and Growth Factor Involvement.Physiological and pathophysiological bone turnover - role of the immune system.Effects of oncostatin M on cell proliferation and osteogenic differentiation in C3H10T1/2 Daily parathyroid hormone administration enhances bone turnover and preserves bone structure after severe immobilization-induced bone loss.N-cadherin restrains PTH activation of Lrp6/β-catenin signaling and osteoanabolic action.Immunology of Gut-Bone Signaling.Bone and the Immune System.Regulatory T cells are expanded by Teriparatide treatment in humans and mediate intermittent PTH-induced bone anabolism in mice.Inflammatory diseases and bone fragility.Reflecting on Some Discoveries of 40 Years and Their Outcomes.CTLA-4Ig (abatacept) balances bone anabolic effects of T cells and Wnt-10b with antianabolic effects of osteoblastic sclerostin.Treatment with intermittent PTH increases Wnt10b production by T cells in osteoporotic patients.Efficacy of a sclerostin antibody compared to a low dose of PTH on metaphyseal bone healing.Suppression of p38α MAPK Signaling in Osteoblast Lineage Cells Impairs Bone Anabolic Action of Parathyroid Hormone.

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P2860

Silencing of parathyroid hormone (PTH) receptor 1 in T cells blunts the bone anabolic activity of PTH

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Silencing of parathyroid hormo ...... bone anabolic activity of PTH

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Silencing of parathyroid hormo ...... bone anabolic activity of PTH

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Brahmchetna Bedi

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Hesham Tawfeek

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Jau-Yi Li

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Jonathan Adams

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Ki-Hyun Baek

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M Neale Weitzmann

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Michaela Kneissel

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Ming-Kang Chang

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Roberto Pacifici

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Sameera S Vangara

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P2860

CD40 ligand blocks apoptosis induced by tumor necrosis factor alpha, glucocorticoids, and etoposide in osteoblasts and the osteocyte-like cell line murine long bone osteocyte-Y4

T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling

The Wnt antagonist secreted frizzled-related protein-1 controls osteoblast and osteocyte apoptosis

Control of bone mass and remodeling by PTH receptor signaling in osteocytes

Molecular determinants of tuberoinfundibular peptide of 39 residues (TIP39) selectivity for the parathyroid hormone-2 (PTH2) receptor. N-terminal truncation of TIP39 reverses PTH2 receptor/PTH1 receptor binding selectivity

TIP39: a new neuropeptide and PTH2-receptor agonist from hypothalamus

Skeletal remodeling in health and disease

Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis

Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

Regulation of osteoblastogenesis and bone mass by Wnt10b

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