Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance. - Test2 - elhamkhani - TriplyDB

Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance.

Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance.

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Recent progress in genetic and epigenetic research on type 2 diabetes Heterogeneity of white adipose tissue: molecular basis and clinical implications Epigenetic Regulation of Chondrocyte Catabolism and Anabolism in Osteoarthritis Vitamin E Modifies High-Fat Diet-Induced Increase of DNA Strand Breaks, and Changes in Expression and DNA Methylation of Dnmt1 and MLH1 in C57BL/6J Male Mice.Impact of brown rice-specific γ-oryzanol on epigenetic modulation of dopamine D2 receptors in brain striatum in high-fat-diet-induced obesity in mice A Memory of Early Life Physical Activity Is Retained in Bone Marrow of Male Rats Fed a High-Fat Diet.Obesity: A Growing Multifaceted Problem Obesity Associated Modulation of miRNA and Co-Regulated Target Transcripts in Human Adipose Tissue of Non-Diabetic Subjects Methylation of insulin DNA in response to proinflammatory cytokines during the progression of autoimmune diabetes in NOD mice.Serum Galanin Levels in Young Healthy Lean and Obese Non-Diabetic Men during an Oral Glucose Tolerance Test.Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis.Interaction between β-hexachlorocyclohexane and ADIPOQ genotypes contributes to the risk of type 2 diabetes mellitus in East Chinese adults.Equine metabolic syndrome impairs adipose stem cells osteogenic differentiation by predominance of autophagy over selective mitophagy.Innate Immunity of Adipose Tissue in Rodent Models of Local and Systemic Staphylococcus aureus Infection.Obesity is associated with depot-specific alterations in adipocyte DNA methylation and gene expression.DNA methylation of tumor necrosis factor-α, monocyte chemoattractant protein-1, and adiponectin genes in visceral adipose tissue is related to type 2 diabetes in the Xinjiang Uygur population.A decrease in hepatic microRNA-9 expression impairs gluconeogenesis by targeting FOXO1 in obese mice.Hoxa5 undergoes dynamic DNA methylation and transcriptional repression in the adipose tissue of mice exposed to high-fat diet.CPT1A methylation is associated with plasma adiponectin.Epigenomic and transcriptional control of insulin resistance.DNA Methyltransferase Inhibitors: Development and Applications.Adipose-derived lipocalin 14 alleviates hyperglycaemia by suppressing both adipocyte glycerol efflux and hepatic gluconeogenesis in mice.Epigenetic Regulation of Adipokines.ColXV promotes adipocyte differentiation via inhibiting DNA methylation and cAMP/PKA pathway in mice Cross Talk between Adipose Tissue and Placenta in Obese and Gestational Diabetes Mellitus Pregnancies via Exosomes.Epigenetic reprogramming in metabolic disorders: nutritional factors and beyond.Dnmt3a is an epigenetic mediator of adipose insulin resistance.Prolonged Exposures to Intermittent Hypoxia Promote Visceral White Adipose Tissue Inflammation in a Murine Model of Severe Sleep Apnea: Effect of Normoxic Recovery.Adiponectin receptor agonists inhibit leptin induced pSTAT3 and in vivo pancreatic tumor growth.Differential metabolic effects of constant moderate versus high intensity interval training in high-fat fed mice: possible role of muscle adiponectin.Adiponectin-Resistance in Obesity.Human liver epigenetic alterations in non-alcoholic steatohepatitis are related to insulin action.Human adipogenesis is associated with genome-wide DNA methylation and gene-expression changes.Construction and Analysis of an Adipose Tissue-Specific and Methylation-Sensitive Promoter of Leptin Gene.Distinct signalling properties of insulin receptor substrate (IRS)-1 and IRS-2 in mediating insulin/IGF-1 action.Metabolomic and microarray analyses of adipose tissue of dapagliflozin-treated mice, and effects of 3-hydroxybutyrate on induction of adiponectin in adipocytes.Regulatory Roles of Invariant Natural Killer T Cells in Adipose Tissue Inflammation: Defenders Against Obesity-Induced Metabolic Complications.The adiponectin promoter activator NP-1 induces high levels of circulating TNFα and weight loss in obese (fa/fa) Zucker rats.Circulating miR-148a associates with sensitivity to adiponectin levels in human metabolic surgery for weight loss

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Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance.

http://www.wikidata.org/entity/Q35863452

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

@zh-cn

name

Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance.

@ast

Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance.

@en

type

label

Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance.

@ast

Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance.

@en

prefLabel

Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance.

@ast

Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance.

@en

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Nature Communications

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Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance.

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A Young Kim

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Abdulelah F Bassas

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Aimin Xu

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Kyong Soo Park

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Kyung Cheul Shin

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Reem M Sallam

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Soo-Heon Kwak

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Xuebo Pan

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Yoon Jeong Park

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Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response

Regulation of chromatin by histone modifications

Inflammation and metabolic disorders

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

Chromatin remodeling complex interacts with ADD1/SREBP1c to mediate insulin-dependent regulation of gene expression

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

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10.1038/NCOMMS8585

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6

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Assim A Alfadda

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2015-07-03T00:00:00Z

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280030436

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1030043378

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26139044

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