A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes.
about
New developments in anti-malarial target candidate and product profilesBioluminescence Method for In Vitro Screening of Plasmodium Transmission-Blocking Compounds.A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.An ultrasensitive NanoLuc-based luminescence system for monitoring Plasmodium berghei throughout its life cycleAnalysis of the dose-dependent stage-specific in vitro efficacy of a multi-stage malaria vaccine candidate cocktail.An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines.Metabolomic Profiling of the Malaria Box Reveals Antimalarial Target Pathways.The need to compare: assessing the level of agreement of three high-throughput assays against Plasmodium falciparum mature gametocytes.Phenotypic Screens in Antimalarial Drug Discovery.The use of transgenic parasites in malaria vaccine research.A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.Modelling mosquito infection at natural parasite densities identifies drugs targeting EF2, PI4K or ATP4 as key candidates for interrupting malaria transmission.Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules.Chromatin Accessibility-Based Characterization of the Gene Regulatory Network Underlying Plasmodium falciparum Blood-Stage Development.Artemisone and Artemiside Are Potent Panreactive Antimalarial Agents That Also Synergize Redox Imbalance in Plasmodium falciparum Transmissible Gametocyte StagesAntimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and aA high throughput screen for next-generation leads targeting malaria parasite transmissionStructural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45Screening for potential prophylactics targeting sporozoite motility through the skin
P2860
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P2860
A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
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2015年學術文章
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name
A semi-automated luminescence ...... laria parasites by mosquitoes.
@ast
A semi-automated luminescence ...... laria parasites by mosquitoes.
@en
type
label
A semi-automated luminescence ...... laria parasites by mosquitoes.
@ast
A semi-automated luminescence ...... laria parasites by mosquitoes.
@en
prefLabel
A semi-automated luminescence ...... laria parasites by mosquitoes.
@ast
A semi-automated luminescence ...... laria parasites by mosquitoes.
@en
P2093
P2860
P50
P921
P356
P1433
P1476
A semi-automated luminescence ...... laria parasites by mosquitoes.
@en
P2093
Ben van Schaijk
Didier Leroy
Karin M Koolen
Koen J Dechering
Martijn W Vos
Will J R Stone
P2860
P2888
P356
10.1038/SREP18704
P407
P577
2015-12-21T00:00:00Z