about
Immune mechanisms of protection: can adjuvants rise to the challenge?Viral immune evasion due to persistence of activated T cells without effector functionVisualization of cytolytic T cell differentiation and granule exocytosis with T cells from mice expressing active fluorescent granzyme BCD8+ T Cells Require Perforin To Clear West Nile Virus from Infected NeuronsCell therapy for the diseased liver: from stem cell biology to novel models for hepatotropic human pathogensThe immunoproteasome and viral infection: a complex regulator of inflammationPerforin-independent CD8(+) T-cell-mediated cytotoxicity of alveolar epithelial cells is preferentially mediated by tumor necrosis factor-alpha: relative insensitivity to Fas ligand.Type II pneumocyte-CD8+ T-cell interactions. Relationship between target cell cytotoxicity and activation.The effector T cell response to influenza infectionStructural and functional consequences of alveolar cell recognition by CD8(+) T lymphocytes in experimental lung disease.A lung-specific neo-antigen elicits specific CD8+ T cell tolerance with preserved CD4+ T cell reactivity. Implications for immune-mediated lung disease.Why can't cytotoxic T cells handle HIV?Lymphocytic choriomeningitis virus-induced mortality in mice is triggered by edema and brain herniationA multivalent and cross-protective vaccine strategy against arenaviruses associated with human disease.Cell adhesion and the immune system: a case study using earthworms.NK cells and apoptosis.Anti-viral strategies of cytotoxic T lymphocytes are manifested through a variety of granule-bound pathways of apoptosis induction.Cancer resistance of SR/CR mice in the genetic knockout backgrounds of leukocyte effector mechanisms: determinations for functional requirements.A role for perforin in downregulating T-cell responses during chronic viral infection.Fas (CD95)-dependent cell-mediated immunity to Listeria monocytogenes.The relative role of lymphocyte granule exocytosis versus death receptor-mediated cytotoxicity in viral pathophysiologyTheiler's virus infection of perforin-deficient mice.DNA immunization with minigenes: low frequency of memory cytotoxic T lymphocytes and inefficient antiviral protection are rectified by ubiquitination.Fas ligand-mediated lysis of self bystander targets by human papillomavirus-specific CD8+ cytotoxic T lymphocytes.Granzyme A, a noncytolytic component of CD8(+) cell granules, restricts the spread of herpes simplex virus in the peripheral nervous systems of experimentally infected mice.Pathogenesis of herpes simplex virus type 1-induced corneal inflammation in perforin-deficient mice.Thymic tolerance to only one viral protein reduces lymphocytic choriomeningitis virus-induced immunopathology and increases survival in perforin-deficient mice.Protection against polyoma virus-induced tumors is perforin-independentMolecular and cellular mechanisms regulating T and B cell apoptosis through Fas/FasL interaction.Attrition of bystander CD8 T cells during virus-induced T-cell and interferon responsesAlternative mechanisms of respiratory syncytial virus clearance in perforin knockout mice lead to enhanced disease.Perforin-independent beta-cell destruction by diabetogenic CD8(+) T lymphocytes in transgenic nonobese diabetic miceConcerted action of the FasL/Fas and perforin/granzyme A and B pathways is mandatory for the development of early viral hepatitis but not for recovery from viral infection.Direct ex vivo kinetic and phenotypic analyses of CD8(+) T-cell responses induced by DNA immunizationCoverage of related pathogenic species by multivalent and cross-protective vaccine design: arenaviruses as a model systemRegulation and function of T-cell-mediated immunity during Toxoplasma gondii infection.A role for the chemokine RANTES in regulating CD8 T cell responses during chronic viral infectionUpregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivoHost factors influencing viral persistence.Quantitative fluorescence measures for determination of intracellular perforin content.
P2860
Q21245319-A4CFCBD3-6C6E-4B76-9418-86D1A9E56276Q24646943-FE0E7EAF-F5D9-45C2-8452-3FD68BA1B45FQ27312334-CEDC11A7-C722-4FE9-BC60-F7F377771822Q27472780-5C05D06A-DDE0-41E2-994A-44849B616C93Q27487009-1C3038C8-7C00-4054-A065-3FDBD82C3930Q27694656-9E6B9C27-FA0F-486C-B390-742AC835C85CQ30303947-2F3AE161-C5B6-4863-9970-43740772EADBQ30308011-5E5CBD96-56B5-4EF1-9749-B39827CFC8FDQ30361773-AA8F6683-E294-45BF-B51A-3D60B03E2286Q30448788-36E4F6A1-FD09-4CC6-AC20-36CD0E868AC4Q30448835-FB9C39A5-BBA6-4281-A373-241D752A6341Q30453955-8E8E552C-F92E-4551-B324-FE02EE90BAF1Q33510525-E502950B-7356-40F0-8F1C-403F7A831467Q33519507-48F41B8F-DC3E-4B4A-9788-AFC5D232B494Q33547026-DA2E263B-2669-4F97-8623-CE750857C35FQ33547794-EBCACFA2-B3DC-4EAE-A03D-7E83E845E973Q33547796-C5B70A66-E93B-400B-8300-90E087EA80B2Q33548145-6D169F31-7475-40C5-9CC3-8E13A4F5FFD8Q33654274-CCEA4BA6-6F2C-4C9F-8A66-E9F6CF0B6683Q33761193-FA64621B-E99A-4F5D-9C45-754AA6FEA340Q33781851-67D6E517-CF9F-4FA4-BAF5-9992608F8835Q33782953-51B4F45D-E64E-4041-A85E-D61C915580CAQ33784641-8AE68106-CE1C-4E28-8FB0-32D4E8BEF237Q33785691-31EDE484-11B5-4C56-A4A9-C3E0E3B1044AQ33796821-0A78A3E5-BC6E-4863-8ACB-AF2D4D6F5264Q33812978-35132127-9900-4E5F-A5D9-F07A9DD33A5DQ33815802-038C2F96-660B-479A-B843-5E522B325B3DQ33817326-F42F7802-9994-4EE6-BD6E-1C7323604411Q33836328-8B1E2EA0-78D4-47F1-996B-205E1873B28DQ33842424-C9485F07-D3AC-41CB-ACCB-986C4DAE8483Q33847030-36EFA96A-382C-418A-8922-2519F4C867D8Q33849632-0AAD769A-60E2-4E75-A37D-A8966684D35CQ33854729-B3427E28-353B-442C-99D2-A19E4F9299D1Q33873715-1E1F6C4E-A747-4FAF-833E-4C1BA49F1683Q33909096-B90B5875-0DB6-4EA6-A561-6EE4C920F6B6Q33975360-464AD601-83AA-4CF6-91B0-B735EC719B96Q33981265-69F9EC7F-06B6-47D8-93F9-19BEC1A688C7Q34040679-C954D299-7AA5-4A8F-8B64-E8AAD43AEBB5Q34143952-C1D55C55-049C-46A3-B809-AF180C8C9C3DQ34173281-5E4519E2-290B-46CC-9896-085A9A46DB05
P2860
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Immune function in mice lacking the perforin gene
@ast
Immune function in mice lacking the perforin gene
@en
type
label
Immune function in mice lacking the perforin gene
@ast
Immune function in mice lacking the perforin gene
@en
prefLabel
Immune function in mice lacking the perforin gene
@ast
Immune function in mice lacking the perforin gene
@en
P2093
P2860
P356
P1476
Immune function in mice lacking the perforin gene
@en
P2093
C G Kurahara
J L Christensen
M Matloubian
P2860
P304
10854-10858
P356
10.1073/PNAS.91.23.10854
P407
P577
1994-11-01T00:00:00Z