Stereochemical evaluation of the relative activities of the cinchona alkaloids against Plasmodium falciparum

Stereochemical evaluation of the relative activities of the cinchona alkaloids against Plasmodium falciparum

Item
http://www.wikidata.org/entity/Q35885408
The relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloidsThe hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex.How do pseudoenantiomers structurally differ in the gas phase? An IR/UV spectroscopy study of jet-cooled hydroquinine and hydroquinidine.Mutation in the Plasmodium falciparum CRT protein determines the stereospecific activity of antimalarial cinchona alkaloids.Malaria chemotherapeutics part I: History of antimalarial drug development, currently used therapeutics, and drugs in clinical development.Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis.Crystal structure of (-)-mefloquine hydrochloride reveals consistency of configuration with biological activity.Relative to quinine and quinidine, their 9-epimers exhibit decreased cytostatic activity and altered heme binding but similar cytocidal activity versus Plasmodium falciparum.Investigating the activity of quinine analogues versus chloroquine resistant Plasmodium falciparum.Alkoxide coordination of iron(III) protoporphyrin IX by antimalarial quinoline methanols: a key interaction observed in the solid-state and solution.Artemisinin
P2860

Stereochemical evaluation of the relative activities of the cinchona alkaloids against Plasmodium falciparum

Item
http://www.wikidata.org/entity/Q35885408
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Stereochemical evaluation of t ...... against Plasmodium falciparum
@ast
Stereochemical evaluation of t ...... against Plasmodium falciparum
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type
label
Stereochemical evaluation of t ...... against Plasmodium falciparum
@ast
Stereochemical evaluation of t ...... against Plasmodium falciparum
@en
prefLabel
Stereochemical evaluation of t ...... against Plasmodium falciparum
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Stereochemical evaluation of t ...... against Plasmodium falciparum
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P1433
P1476
P2093
P2860
P304
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P356
P407
P433
P478
P577
P5875
P698
P921
P932
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P1433
P1476
Stereochemical evaluation of t ...... against Plasmodium falciparum
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P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932