The importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity.
about
The structure of the human tRNALys3 anticodon bound to the HIV genome is stabilized by modified nucleosides and adjacent mismatch base pairsPrimer tRNAs for reverse transcriptionSelection of functional tRNA primers and primer binding site sequences from a retroviral combinatorial library: identification of new functional tRNA primers in murine leukemia virus replication.The human immunodeficiency virus type 1 Gag polyprotein has nucleic acid chaperone activity: possible role in dimerization of genomic RNA and placement of tRNA on the primer binding site.The nucleocapsid protein specifically anneals tRNALys-3 onto a noncomplementary primer binding site within the HIV-1 RNA genome in vitro.Analysis of the contribution of reverse transcriptase and integrase proteins to retroviral RNA dimer conformation.Changes in Rous sarcoma virus RNA secondary structure near the primer binding site upon tRNATrp primer annealing.Structural basis for the specificity of the initiation of HIV-1 reverse transcription.A succession of mechanisms stimulate efficient reconstituted HIV-1 minus strand strong stop DNA transferInitiation of HIV-2 reverse transcription: a secondary structure model of the RNA-tRNA(Lys3) duplex.Structural and functional properties of the HIV-1 RNA-tRNA(Lys)3 primer complex annealed by the nucleocapsid protein: comparison with the heat-annealed complexMutational analysis of the tRNA3Lys/HIV-1 RNA (primer/template) complex.The Interaction between tRNA(Lys) 3 and the primer activation signal deciphered by NMR spectroscopy.Role of HIV-1 nucleocapsid protein in HIV-1 reverse transcription.The tRNA primer activation signal in the human immunodeficiency virus type 1 genome is important for initiation and processive elongation of reverse transcriptionSynthetic tRNALys,3 as the replication primer for the HIV-1HXB2 and HIV-1Mal genomes.Destabilization of tRNA3(Lys) from the primer-binding site of HIV-1 genome by anti-A loop polyamide nucleotide analogHuman immunodeficiency virus type-1 reverse transcription can be inhibited in vitro by oligonucleotides that target both natural and synthetic tRNA primers.A structured RNA motif is involved in correct placement of the tRNA(3)(Lys) primer onto the human immunodeficiency virus genome.Initiation of HIV Reverse TranscriptionGenetic analysis of a unique human immunodeficiency virus type 1 (HIV-1) with a primer binding site complementary to tRNAMet supports a role for U5-PBS stem-loop RNA structures in initiation of HIV-1 reverse transcriptionSpecific and independent recognition of U3 and U5 att sites by human immunodeficiency virus type 1 integrase in vivo.Roles of the human immunodeficiency virus type 1 nucleocapsid protein in annealing and initiation versus elongation in reverse transcription of viral negative-strand strong-stop DNAImpact of human immunodeficiency virus type 1 RNA dimerization on viral infectivity and of stem-loop B on RNA dimerization and reverse transcription and dissociation of dimerization from packaging.Stabilization of the U5-leader stem in the HIV-1 RNA genome affects initiation and elongation of reverse transcriptionTransfer of primer binding site-mutated simian immunodeficiency virus vectors by genetically engineered artificial and hybrid tRNA-like primers.Forced selection of a human immunodeficiency virus type 1 variant that uses a non-self tRNA primer for reverse transcription: involvement of viral RNA sequences and the reverse transcriptase enzyme.Switching the in vitro tRNA usage of HIV-1 by simultaneous adaptation of the PBS and PAS.Role of the primer activation signal in tRNA annealing onto the HIV-1 genome studied by single-molecule FRET microscopy.Identification of a sequence element immediately upstream of the polypurine tract that is essential for replication of simian immunodeficiency virus.Genetic analysis of the U5-PBS of a novel HIV-1 reveals multiple interactions between the tRNA and RNA genome required for initiation of reverse transcription.Architecture of an HIV-1 reverse transcriptase initiation complex.
P2860
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P2860
The importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
The importance of the A-rich l ...... transcription and infectivity.
@ast
The importance of the A-rich l ...... transcription and infectivity.
@en
type
label
The importance of the A-rich l ...... transcription and infectivity.
@ast
The importance of the A-rich l ...... transcription and infectivity.
@en
prefLabel
The importance of the A-rich l ...... transcription and infectivity.
@ast
The importance of the A-rich l ...... transcription and infectivity.
@en
P2093
P2860
P1433
P1476
The importance of the A-rich l ...... transcription and infectivity
@en
P2093
Wainberg MA
P2860
P304
P407
P577
1997-08-01T00:00:00Z