TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma. - Test2 - elhamkhani - TriplyDB

TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.

TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.

http://www.wikidata.org/entity/Q35892567

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The emerging insights into catalytic or non-catalytic roles of TET proteins in tumors and neural development Multiple Functions of Ten-eleven Translocation 1 during Tumorigenesis Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes Epigenetic Therapy for Solid Tumors: Highlighting the Impact of Tumor Hypoxia Ascorbate as a co-factor for fe- and 2-oxoglutarate dependent dioxygenases: physiological activity in tumor growth and progression Air pollution, epigenetics, and asthma Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA.Epigenetic programming of hypoxic-ischemic encephalopathy in response to fetal hypoxia.Oxygen concentration controls epigenetic effects in models of familial paraganglioma.Novel Epigenetic Controlling of Hypoxia Pathway Related to Overexpression and Promoter Hypomethylation of TET1 and TET2 in RPE Cells.TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer Epigenetics, TET proteins, and hypoxia in epithelial-mesenchymal transition and tumorigenesis Ten-eleven translocation 1 (TET1) methylation is associated with childhood asthma and traffic-related air pollution.Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells.Tumour hypoxia causes DNA hypermethylation by reducing TET activity.Regulation of HK2 expression through alterations in CpG methylation of the HK2 promoter during progression of hepatocellular carcinoma.New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine.The Mechanism and Function of Epigenetics in Uterine Leiomyoma Development.Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.Hypoxia-induced TET1 facilitates trophoblast cell migration and invasion through HIF1α signaling pathway.The Emerging Role of DNA Methylation in Kidney Transplantation: A Perspective.Hypoxia-Mediated Epigenetic Regulation of Stemness in Brain Tumor Cells.TET1 promotes cisplatin-resistance via demethylating the vimentin promoter in ovarian cancer.The α-ketoglutarate dehydrogenase complex in cancer metabolic plasticity.The epigenetic landscape related to reactive oxygen species formation in the cardiovascular system.Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients.Aberrant methylation of MUC1 and MUC4 promoters are potential prognostic biomarkers for pancreatic ductal adenocarcinomas.Association of TET1 expression with colorectal cancer progression.miR-25/93 mediates hypoxia-induced immunosuppression by repressing cGAS.High levels of 5-hydroxymethylcytosine (5hmC) is an adverse predictor of biochemical recurrence after prostatectomy in ERG-negative prostate cancer Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways.Metabostemness: Metaboloepigenetic reprogramming of cancer stem-cell functions.Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity.Potential role of the methylation of VEGF gene promoter in response to hypoxia in oxygen-induced retinopathy: beneficial effect of the absence of AQP4.Hypoxia induces the expression of TET enzymes in HepG2 cells.Integrating 5hmC and gene expression data to infer regulatory mechanisms.Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation.The TET enzymes.Consequences of VHL Loss on Global DNA Methylome.

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TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.

http://www.wikidata.org/entity/Q35892567

description

2014 nî lūn-bûn

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2014年の論文

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2014年论文

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2014年论文

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2014年论文

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name

TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.

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TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.

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type

label

TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.

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TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.

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prefLabel

TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.

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TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.

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J.CELREP.2014.04.040

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TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.

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Ali Yesilkanal

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Amit Verma

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Aparna Vasanthakumar

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Christopher J Mariani

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Jayasri Nanduri

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Jozef Madzo

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Lucy A Godley

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Nanduri R Prabhakar

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Roland H Wenger

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Sanchari Bhattacharyya

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P2860

Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates

The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

An integrated encyclopedia of DNA elements in the human genome

HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

Hypoxia-inducible factors and the response to hypoxic stress

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells

Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming

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