Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)
about
Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response.Checkpoint kinase 1 inhibition sensitises transformed cells to dihydroorotate dehydrogenase inhibition.N,N-disubstituted azines attenuate LPS-mediated neuroinflammation in microglia and neuronal apoptosis via inhibiting MAPK signaling pathways.A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
P2860
Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)
description
2015 nî lūn-bûn
@nan
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
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2015年論文
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2015年论文
@wuu
2015年论文
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2015年论文
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name
Original 2-(3-Alkoxy-1H-pyrazo ...... oorotate Dehydrogenase (DHODH)
@ast
Original 2-(3-Alkoxy-1H-pyrazo ...... oorotate Dehydrogenase (DHODH)
@en
type
label
Original 2-(3-Alkoxy-1H-pyrazo ...... oorotate Dehydrogenase (DHODH)
@ast
Original 2-(3-Alkoxy-1H-pyrazo ...... oorotate Dehydrogenase (DHODH)
@en
prefLabel
Original 2-(3-Alkoxy-1H-pyrazo ...... oorotate Dehydrogenase (DHODH)
@ast
Original 2-(3-Alkoxy-1H-pyrazo ...... oorotate Dehydrogenase (DHODH)
@en
P2093
P2860
P50
P1476
Original 2-(3-Alkoxy-1H-pyrazo ...... oorotate Dehydrogenase (DHODH)
@en
P2093
Artur Scherf
Farah El Mazouni
Jane Harpon
Margaret A Phillips
Marianne Lucas-Hourani
Olivier Helynck
Sandrine Guillou
P2860
P304
P356
10.1021/ACS.JMEDCHEM.5B00606
P407
P50
P577
2015-06-30T00:00:00Z