Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus
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A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus InfectionRespiratory virus modulation of host nucleocytoplasmic transport; target for therapeutic intervention?Plasmodium falciparum signal recognition particle components and anti-parasitic effect of ivermectin in blocking nucleo-cytoplasmic shuttling of SRP.Personalization of the immunosuppressive treatment in renal transplant recipients: the great challenge in "omics" medicineA viral-human interactome based on structural motif-domain interactions captures the human infectomeDengue therapeutics, chemoprophylaxis, and allied tools: state of the art and future directionsSelective Inhibitor of Nuclear Export (SINE) Compounds Alter New World Alphavirus Capsid Localization and Reduce Viral Replication in Mammalian CellsThe p53-induced factor Ei24 inhibits nuclear import through an importin β-binding-like domainThe IMPORTance of the Nucleus during Flavivirus Replication.Ivermectin - Old Drug, New Tricks?Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import.Microbial Natural Product Alternariol 5-O-Methyl Ether Inhibits HIV-1 Integration by Blocking Nuclear Import of the Pre-Integration Complex.HE4 expression is associated with hormonal elements and mediated by importin-dependent nuclear translocationRole of a nuclear localization signal on the minor capsid proteins VP2 and VP3 in BKPyV nuclear entry.Bridging HIV-1 cellular latency and clinical long-term non-progressor: an interactomic viewcGMP-dependent protein kinase I gamma encodes a nuclear localization signal that regulates nuclear compartmentation and function.Identification of a functional nuclear localization signal mediating nuclear import of the zinc finger transcription factor ZNF24Coordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal.Karyopherins: potential biological elements involved in the delayed graft function in renal transplant recipients.Aedes aegypti (L.) survival after exposure to ivermectinInfluenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I.Distinct terminal and cell body mechanisms in the nociceptor mediate hyperalgesic primingDiversification of importin-α isoforms in cellular trafficking and disease statesSelective Targeting of the TPX2 Site of Importin-α Using Fragment-Based Ligand Design.Benzothiazole and Pyrrolone Flavivirus Inhibitors Targeting the Viral Helicase.Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines.The Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication SitesNuclear Trafficking of the Rabies Virus Interferon Antagonist P-Protein Is Regulated by an Importin-Binding Nuclear Localization Sequence in the C-Terminal Domain.Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.Ivermectin inhibits the sporogony of Plasmodium falciparum in Anopheles gambiae.Dynamic Nucleolar Targeting of Dengue Virus Polymerase NS5 in Response to Extracellular pHNuclear glutaredoxin 3 is critical for protection against oxidative stress-induced cell deathRegulated transport into the nucleus of herpesviridae DNA replication core proteins.Serotype-specific differences in dengue virus non-structural protein 5 nuclear localizationNuclear translocation of annexin 1 following oxygen-glucose deprivation-reperfusion induces apoptosis by regulating Bid expression via p53 binding.The PPE2 protein of Mycobacterium tuberculosis translocates to host nucleus and inhibits nitric oxide production.Targeting host factors to treat West Nile and dengue viral infections.West Nile virus drug discovery.The function of importin β1 is conserved in eukaryotes but the substrates may vary in organisms.Induction of nuclear translocation of mutant cytoplasmic p53 by geranylgeranoic acid in a human hepatoma cell line.
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Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Ivermectin is a specific inhib ...... tion of HIV-1 and dengue virus
@ast
Ivermectin is a specific inhib ...... tion of HIV-1 and dengue virus
@en
type
label
Ivermectin is a specific inhib ...... tion of HIV-1 and dengue virus
@ast
Ivermectin is a specific inhib ...... tion of HIV-1 and dengue virus
@en
prefLabel
Ivermectin is a specific inhib ...... tion of HIV-1 and dengue virus
@ast
Ivermectin is a specific inhib ...... tion of HIV-1 and dengue virus
@en
P2860
P50
P921
P356
P1433
P1476
Ivermectin is a specific inhib ...... tion of HIV-1 and dengue virus
@en
P2093
David Harrich
P2860
P304
P356
10.1042/BJ20120150
P407
P577
2012-05-01T00:00:00Z