A novel rare variant in SCN1Bb linked to Brugada syndrome and SIDS by combined modulation of Na(v)1.5 and K(v)4.3 channel currents.
about
Channelopathies from mutations in the cardiac sodium channel protein complexSudden unexplained death in infants and children: the role of undiagnosed inherited cardiac conditionsJ-wave syndromes: Brugada and early repolarization syndromesOn the multiple roles of the voltage gated sodium channel β1 subunit in genetic diseasesSodium channel β subunits: emerging targets in channelopathiesAbnormal repolarization as the basis for late potentials and fractionated electrograms recorded from epicardium in experimental models of Brugada syndrome.Enhanced risk profiling of implanted defibrillator shocks with circulating SCN5A mRNA splicing variants: a pilot trial.Brugada syndrome risk loci seem protective against atrial fibrillation.J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledgeAssigning cause for sudden unexpected infant death.Novel heterozygous mutation c.4282G>T in the SCN5A gene in a family with Brugada syndromeThe Role of Pharmacogenetics in Atrial Fibrillation Therapeutics: Is Personalized Therapy in Sight?Cardiac ion channelopathies and the sudden infant death syndromeBrugada Syndrome: Clinical, Genetic, Molecular, Cellular, and Ionic Aspects.Spectrum and prevalence of mutations involving BrS1- through BrS12-susceptibility genes in a cohort of unrelated patients referred for Brugada syndrome genetic testing: implications for genetic testing.Cellular and ionic mechanisms underlying the effects of cilostazol, milrinone, and isoproterenol to suppress arrhythmogenesis in an experimental model of early repolarization syndrome.The genetic component of Brugada syndromeNovel Therapeutic Strategies for the Management of Ventricular Arrhythmias Associated with the Brugada SyndromeCellular mechanisms underlying the effects of milrinone and cilostazol to suppress arrhythmogenesis associated with Brugada syndrome.Unfolded protein response regulates cardiac sodium current in systolic human heart failureAtrial fibrillation: the role of common and rare genetic variants.Modulatory mechanisms and multiple functions of somatodendritic A-type K (+) channel auxiliary subunitsSCN1B gene variants in Brugada Syndrome: a study of 145 SCN5A-negative patientsCurrent perspectives in genetic cardiovascular disorders: from basic to clinical aspects.KCNE4 and KCNE5: K(+) channel regulation and cardiac arrhythmogenesis.Histone Deacetylase Inhibitors Prolong Cardiac Repolarization through Transcriptional Mechanisms.Mechanisms of noncovalent β subunit regulation of NaV channel gating.A missense mutation in the sodium channel β2 subunit reveals SCN2B as a new candidate gene for Brugada syndrome.Sudden cardiac death in the young: how can disease recognition and prevention in family members be improved?Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.Regulation of Cardiac Voltage-Gated Sodium Channel by Kinases: Roles of Protein Kinases A and C.Voltage-Gated Sodium Channel β Subunits and Their Related Diseases.Scn1b deletion leads to increased tetrodotoxin-sensitive sodium current, altered intracellular calcium homeostasis and arrhythmias in murine hearts.Infant sudden death: Mutations responsible for impaired Nav1.5 channel trafficking and function.Sudden infant death syndrome and inherited cardiac conditions.Cardiac channelopathies associated with infantile fatal ventricular arrhythmias: from the cradle to the bench.KV4.3 Expression Modulates NaV1.5 Sodium Current.J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge.Voltage-Gated Sodium Channel β1/β1B Subunits Regulate Cardiac Physiology and Pathophysiology.Functional implications of a rare variant in the sodium channel β1B subunit (SCN1B) in a 5-month-old male sudden infant death syndrome case.
P2860
Q26824051-7D14AB19-7DB9-480D-93F7-91F34177939FQ26827729-DECC16D5-7B9C-4BAF-9E8A-C92B3A81EB26Q26859366-3109F08E-96A9-46D1-9E77-E81914C971F8Q28080803-B59BDF5D-0C62-43B6-8045-EB3A99FD27CCQ28082122-3AA0358C-D770-401D-AD84-8663AF3DC645Q33625055-36DB667C-C7E5-4F09-9E2E-9FBB03E926CFQ33896741-D864F7EC-5DB1-4C9C-BAA7-AF4A28879EE0Q34508291-AB6E5277-3815-4079-896C-DBB725EA2C78Q34534329-CE966B7F-F200-406B-AD18-F70E69ECDA91Q35558408-CF37B288-B0B1-4E4B-99AC-66106584BDE9Q35754059-EB5519B7-6758-4E8C-B7A3-8A1C0B43894BQ36264955-6312C792-1DCE-4754-AC5C-830CA9439630Q36486478-580A04D2-9927-4008-9D3E-D1390041B453Q36534132-A37FBC28-C76B-43AF-B082-2A8F0356991BQ36761139-A3E7B165-0D4C-4954-B78F-B92C961970A0Q36932457-59DC9202-3ED2-43DF-B357-4F94C228AC56Q37011109-52BBA555-E2A2-440D-9969-6F442A1CD58BQ37194514-7DF3A1A0-905A-4022-84AA-D260C274C5EBQ37302824-CF72B304-6566-46F2-9BC9-3EDE345FB4D8Q37540104-01F80486-2C54-4844-8DAE-A3B40FF62E01Q37585850-AFB285A6-A021-4CED-80DF-6BC7DA6B8D3EQ37681403-9F1EFE03-2C82-46B6-BE05-C710605091E8Q37734653-017B4920-3EEA-403A-8F08-E4BBC8074FFCQ38125941-8BD3BF03-3F2D-4AB4-93D1-2954AE0BA66CQ38916407-8487DAB6-B06E-4C8E-9C3E-BBB8B1E0C2DFQ39714637-A498CF11-EE7F-4E21-9911-55FCD6083F88Q41445181-A4680A79-B423-43A0-B851-8A7D5C12B8BDQ44515706-EE2334A2-12B3-4A42-A616-B0C4A8F06190Q44701011-E20FD400-8B8D-4F62-90D8-3166B6DA822CQ45088273-3D1E29AD-361B-4201-93F8-807F7E59A753Q47651784-FA180F94-ABED-4BB8-9211-AE45C28F699BQ47720312-A50C8497-6749-4426-AB9D-EA8D0757B549Q47736002-4DD92DC4-D593-4EA2-8888-9860FC28BE6AQ47746225-8A0AC042-0294-43D4-9531-A1D300071E13Q50208657-F1BE766F-9880-41E7-A0C4-083EDE64430EQ51751600-08724144-4853-47B4-9358-5FAFB4F1B82FQ52624657-55CB2E0D-0873-4FEA-A1BF-151C7DE96B9CQ55059903-54AA73B1-2D12-4BBA-B751-E394708945D4Q55279100-CEE6D589-184E-4266-8498-15E3C5F73BD4Q55339082-486A163C-C41E-45D6-896A-DC774F3F85F7
P2860
A novel rare variant in SCN1Bb linked to Brugada syndrome and SIDS by combined modulation of Na(v)1.5 and K(v)4.3 channel currents.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
A novel rare variant in SCN1Bb ...... and K(v)4.3 channel currents.
@ast
A novel rare variant in SCN1Bb ...... and K(v)4.3 channel currents.
@en
type
label
A novel rare variant in SCN1Bb ...... and K(v)4.3 channel currents.
@ast
A novel rare variant in SCN1Bb ...... and K(v)4.3 channel currents.
@en
prefLabel
A novel rare variant in SCN1Bb ...... and K(v)4.3 channel currents.
@ast
A novel rare variant in SCN1Bb ...... and K(v)4.3 channel currents.
@en
P2093
P2860
P50
P1433
P1476
A novel rare variant in SCN1Bb ...... and K(v)4.3 channel currents.
@en
P2093
Aintzane Alday
Christian Veltmann
David J Tester
Elena Burashnikov
Gabriel Caceres
Hector Barajas-Martínez
Janire Urrutia
Michael J Ackerman
Oscar Casis
P2860
P304
P356
10.1016/J.HRTHM.2011.12.006
P50
P577
2011-12-07T00:00:00Z