Zinc finger-DNA recognition: analysis of base specificity by site-directed mutagenesis
about
Toward a code for the interactions of zinc fingers with DNA: selection of randomized fingers displayed on phageBuilding zinc fingers by selection: toward a therapeutic applicationGfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressorDNA-binding specificity of NGFI-A and related zinc finger transcription factorsReciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autismToward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequencesProtein design: toward functional metalloenzymesCharacterization of three related glucose repressors and genes they regulate in Saccharomyces cerevisiae.Importance of a flanking AT-rich region in target site recognition by the GC box-binding zinc finger protein MIG1.Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteinsDevelopment of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factorsEngineering polydactyl zinc-finger transcription factorsCloning and characterization of a transcription factor that binds to the proximal promoters of the two mouse type I collagen genesHoxb-2 transcriptional activation in rhombomeres 3 and 5 requires an evolutionarily conserved cis-acting element in addition to the Krox-20 binding sitePhenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors.Cys2/His2 zinc-finger protein family of petunia: evolution and general mechanism of target-sequence recognition.Local gene regulation details a recognition code within the LacI transcriptional factor family.Identification of a frameshift mutation in Osterix in a patient with recessive osteogenesis imperfecta.The two zinc finger-like domains of GATA-1 have different DNA binding specificitiesTranscriptional regulation of the MHC class I HLA-A11 promoter by the zinc finger protein ZFX.A single amino-acid substitution in the Ets domain alters core DNA binding specificity of Ets1 to that of the related transcription factors Elf1 and E74.Locus-wide identification of Egr2/Krox20 regulatory targets in myelin genesSynthetic zinc finger peptides: old and novel applications.A zinc finger directory for high-affinity DNA recognition.The single Cys2-His2 zinc finger domain of the GAGA protein flanked by basic residues is sufficient for high-affinity specific DNA binding.Recognition of diverse sequences by class I zinc fingers: asymmetries and indirect effects on specificity in the interaction between CF2II and A+T-rich elementsDNA recognition by splicing variants of the Wilms' tumor suppressor, WT1Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleasesStereochemical basis of DNA recognition by Zn fingers.Two different, adjacent and divergent zinc finger binding sites are necessary for CREA-mediated carbon catabolite repression in the proline gene cluster of Aspergillus nidulans.Zinc is essential for high-affinity DNA binding and recombinase activity of ΦC31 integrasePrediction of DNA-binding proteins from relational features.Dissection of a Krox20 positive feedback loop driving cell fate choices in hindbrain patterning.Single zinc-finger extension: enhancing transcriptional activity and specificity of three-zinc-finger proteins.Target-sequence recognition by separate-type Cys2/His2 zinc finger proteins in plants.Cooperation, cis-interactions, versatility and evolutionary plasticity of multiple cis-acting elements underlie krox20 hindbrain regulationFrom repression domains to designer zinc finger proteins: a novel strategy of intracellular immunization against HIV
P2860
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P2860
Zinc finger-DNA recognition: analysis of base specificity by site-directed mutagenesis
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Zinc finger-DNA recognition: analysis of base specificity by site-directed mutagenesis
@ast
Zinc finger-DNA recognition: analysis of base specificity by site-directed mutagenesis
@en
type
label
Zinc finger-DNA recognition: analysis of base specificity by site-directed mutagenesis
@ast
Zinc finger-DNA recognition: analysis of base specificity by site-directed mutagenesis
@en
prefLabel
Zinc finger-DNA recognition: analysis of base specificity by site-directed mutagenesis
@ast
Zinc finger-DNA recognition: analysis of base specificity by site-directed mutagenesis
@en
P2093
P2860
P356
P1476
Zinc finger-DNA recognition: analysis of base specificity by site-directed mutagenesis
@en
P2093
P2860
P304
P356
10.1093/NAR/20.16.4137
P407
P577
1992-08-01T00:00:00Z