Removal of vaccinia virus genes that block interferon type I and II pathways improves adaptive and memory responses of the HIV/AIDS vaccine candidate NYVAC-C in mice
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Nonhuman primate models for HIV/AIDS vaccine developmentPoxvirus vectors as HIV/AIDS vaccines in humansThe evolution of poxvirus vaccinesDeletion of the vaccinia virus gene A46R, encoding for an inhibitor of TLR signalling, is an effective approach to enhance the immunogenicity in mice of the HIV/AIDS vaccine candidate NYVAC-CThe influence of delivery vectors on HIV vaccine efficacyDeletion of the viral anti-apoptotic gene F1L in the HIV/AIDS vaccine candidate MVA-C enhances immune responses against HIV-1 antigensImproving Adaptive and Memory Immune Responses of an HIV/AIDS Vaccine Candidate MVA-B by Deletion of Vaccinia Virus Genes (C6L and K7R) Blocking Interferon Signaling PathwaysVirological and immunological characterization of novel NYVAC-based HIV/AIDS vaccine candidates expressing clade C trimeric soluble gp140(ZM96) and Gag(ZM96)-Pol-Nef(CN54) as virus-like particles.Interleukin-1- and type I interferon-dependent enhanced immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef vaccine vector with dual deletions of type I and type II interferon-binding proteins.Head-to-Head Comparison of Poxvirus NYVAC and ALVAC Vectors Expressing Identical HIV-1 Clade C Immunogens in Prime-Boost Combination with Env Protein in Nonhuman PrimatesAttenuation of monkeypox virus by deletion of genomic regionsPotential To Streamline Heterologous DNA Prime and NYVAC/Protein Boost HIV Vaccine Regimens in Rhesus Macaques by Employing Improved AntigensCD4+ T cells provide intermolecular help to generate robust antibody responses in vaccinia virus-vaccinated humans.Enhancing poxvirus vectors vaccine immunogenicity.Vaccinia virus protein K7 is a virulence factor that alters the acute immune response to infectionReflections on the early development of poxvirus vectors.Increased attenuation but decreased immunogenicity by deletion of multiple vaccinia virus immunomodulators.The canarypox virus vector ALVAC induces distinct cytokine responses compared to the vaccinia virus-based vectors MVA and NYVAC in rhesus monkeys.Deletion of the vaccinia virus N2L gene encoding an inhibitor of IRF3 improves the immunogenicity of modified vaccinia virus Ankara expressing HIV-1 antigens.Vaccinia virus inhibits NF-κB-dependent gene expression downstream of p65 translocation.RNA-Seq Based Transcriptome Analysis of the Type I Interferon Host Response upon Vaccinia Virus Infection of Mouse CellsA heterologous prime-boosting strategy with replicating Vaccinia virus vectors and plant-produced HIV-1 Gag/dgp41 virus-like particles.HIV/AIDS Vaccine Candidates Based on Replication-Competent Recombinant Poxvirus NYVAC-C-KC Expressing Trimeric gp140 and Gag-Derived Virus-Like Particles or Lacking the Viral Molecule B19 That Inhibits Type I Interferon Activate Relevant HIV-1-SpeciRecombinant fowlpox virus vector-based vaccines: expression kinetics, dissemination and safety profile following intranasal delivery.Deletion of immunomodulator C6 from vaccinia virus strain Western Reserve enhances virus immunogenicity and vaccine efficacy.Immune Modulation of NYVAC-Based HIV Vaccines by Combined Deletion of Viral Genes that Act on Several Signalling Pathways.Modulating Vaccinia Virus Immunomodulators to Improve Immunological Memory.
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P2860
Removal of vaccinia virus genes that block interferon type I and II pathways improves adaptive and memory responses of the HIV/AIDS vaccine candidate NYVAC-C in mice
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Removal of vaccinia virus gene ...... cine candidate NYVAC-C in mice
@ast
Removal of vaccinia virus gene ...... cine candidate NYVAC-C in mice
@en
type
label
Removal of vaccinia virus gene ...... cine candidate NYVAC-C in mice
@ast
Removal of vaccinia virus gene ...... cine candidate NYVAC-C in mice
@en
prefLabel
Removal of vaccinia virus gene ...... cine candidate NYVAC-C in mice
@ast
Removal of vaccinia virus gene ...... cine candidate NYVAC-C in mice
@en
P2093
P2860
P356
P1433
P1476
Removal of vaccinia virus gene ...... cine candidate NYVAC-C in mice
@en
P2093
Beatriz Perdiguero
Carlos Oscar S Sorzano
Jose Luis Nájera
Mariano Esteban
Rubén González-Sanz
Victoria Jiménez
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P304
P356
10.1128/JVI.06684-11
P407
P577
2012-03-14T00:00:00Z