CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people
about
Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors.The relationship between the nicotine metabolite ratio and three self-report measures of nicotine dependence across sex and race.Precision Medicine for Tobacco Dependence: Development and Validation of the Nicotine Metabolite RatioKnown and novel sources of variability in the nicotine metabolite ratio in a large sample of treatment-seeking smokersVariation in trans-3'-hydroxycotinine glucuronidation does not alter the nicotine metabolite ratio or nicotine intake.Characterization of CYP2B6 in a CYP2B6-humanized mouse model: inducibility in the liver by phenobarbital and dexamethasone and role in nicotine metabolism in vivoBiomarkers of Response to Smoking Cessation Pharmacotherapies: Progress to Date.Nicotine metabolite ratio (3-hydroxycotinine/cotinine) in plasma and urine by different analytical methods and laboratories: implications for clinical implementation.Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation.Pilot study of CYP2B6 genetic variation to explore the contribution of nitrosamine activation to lung carcinogenesis.Influence of CYP2B6 genetic variants on plasma and urine concentrations of bupropion and metabolites at steady state.CHRNA5-A3-B4 genetic variants alter nicotine intake and interact with tobacco use to influence body weight in Alaska Native tobacco users.Novel CYP2A6 variants identified in African Americans are associated with slow nicotine metabolism in vitro and in vivo.Distribution of polymorphic variants of CYP2A6 and their involvement in nicotine addiction.CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study.Nicotine Metabolite Ratio Is Associated With Lozenge Use But Not Quitting in Smokeless Tobacco Users.CYP2A6 genotyping methods and strategies using real-time and end point PCR platforms.High tobacco use prevalence with significant regional and sex differences in smokeless tobacco use among Western Alaska Native people: the WATCH study.Variation in CYP2A6 Activity and Personalized Medicine.P450 Pharmacogenetics in Indigenous North American Populations.Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism.Variation in CYP2A6 and nicotine metabolism among two American Indian tribal groups differing in smoking patterns and risk for tobacco-related cancer.
P2860
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P2860
CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
CYP2A6 and CYP2B6 genetic vari ...... h Western Alaska Native people
@ast
CYP2A6 and CYP2B6 genetic vari ...... h Western Alaska Native people
@en
type
label
CYP2A6 and CYP2B6 genetic vari ...... h Western Alaska Native people
@ast
CYP2A6 and CYP2B6 genetic vari ...... h Western Alaska Native people
@en
prefLabel
CYP2A6 and CYP2B6 genetic vari ...... h Western Alaska Native people
@ast
CYP2A6 and CYP2B6 genetic vari ...... h Western Alaska Native people
@en
P2093
P2860
P1476
CYP2A6 and CYP2B6 genetic vari ...... h Western Alaska Native people
@en
P2093
Andy Z X Zhu
Caroline C Renner
Dorothy K Hatsukami
Matthew J Binnington
Neal L Benowitz
Rachel F Tyndale
P2860
P304
P356
10.1097/FPC.0B013E3283527C1C
P577
2012-06-01T00:00:00Z