Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis.
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Metabolism leaves its mark on the powerhouse: recent progress in post-translational modifications of lysine in mitochondriaMetabolism, longevity and epigeneticsSIRT3 as a Regulator of Non-alcoholic Fatty Liver DiseaseSirtuins and nonalcoholic fatty liver diseaseSurface energy-mediated construction of anisotropic semiconductor wires with selective crystallographic polarity.SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts.Sirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections.Sirtuins: guardians of mammalian healthspan.SIRT3 deacetylates ATP synthase F1 complex proteins in response to nutrient- and exercise-induced stress.Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity.Understanding the acetylome: translating targeted proteomics into meaningful physiologyMitochondrial sirtuins and their relationships with metabolic disease and cancer.Using mitochondrial sirtuins as drug targets: disease implications and available compounds.SIRT3 Is Crucial for Maintaining Skeletal Muscle Insulin Action and Protects Against Severe Insulin Resistance in High-Fat-Fed Mice.Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating SirtuinExploring the therapeutic space around NAD+.Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype.Loss of Fatty Acid Binding Protein 4/aP2 Reduces Macrophage Inflammation Through Activation of SIRT3Sirtuin 3 (SIRT3) maintains bone homeostasis by regulating AMPK-PGC-1β axis in mice.The sirtuin family's role in aging and age-associated pathologies.Inhibition of p300 lysine acetyltransferase activity by luteolin reduces tumor growth in head and neck squamous cell carcinoma (HNSCC) xenograft mouse model.Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice.Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes.Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation.Metabolic characterization of a Sirt5 deficient mouse model.An acetylation rheostat for the control of muscle energy homeostasisNAD⁺ metabolism: a therapeutic target for age-related metabolic disease.SIRT3: as simple as it seems?Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development.A metabolic link to skeletal muscle wasting and regeneration.Regulation of autophagy and mitophagy by nutrient availability and acetylation.Turn up the power - pharmacological activation of mitochondrial biogenesis in mouse models.NAD and ADP-ribose metabolism in mitochondria.Protein acetylation in metabolism - metabolites and cofactors.Nicotinamide mononucleotide requires SIRT3 to improve cardiac function and bioenergetics in a Friedreich's ataxia cardiomyopathy modelSirtuin 3 acts as a negative regulator of autophagy dictating hepatocyte susceptibility to lipotoxicity.CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance.SIRT3 Directs Carbon Traffic in Muscle to Promote Glucose Control.SIRT3: A Central Regulator of Mitochondrial Adaptation in Health and Disease.
P2860
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P2860
Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Muscle or liver-specific Sirt3 ...... global metabolic homeostasis.
@ast
Muscle or liver-specific Sirt3 ...... global metabolic homeostasis.
@en
type
label
Muscle or liver-specific Sirt3 ...... global metabolic homeostasis.
@ast
Muscle or liver-specific Sirt3 ...... global metabolic homeostasis.
@en
prefLabel
Muscle or liver-specific Sirt3 ...... global metabolic homeostasis.
@ast
Muscle or liver-specific Sirt3 ...... global metabolic homeostasis.
@en
P2093
P2860
P50
P356
P1433
P1476
Muscle or liver-specific Sirt3 ...... global metabolic homeostasis.
@en
P2093
Eija Pirinen
Ellen H Jeninga
Hiroyasu Yamamoto
Norman Moullan
Pablo J Fernandez-Marcos
Penelope Andreux
Taoufiq Harach
Vincent C J de Boer
P2860
P2888
P356
10.1038/SREP00425
P407
P577
2012-05-28T00:00:00Z