Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record. - Test2 - elhamkhani - TriplyDB

Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record.

Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record.

http://www.wikidata.org/entity/Q35991881

about

Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality Role of genomics in eliminating health disparities Cardiovascular pharmacogenomics: current status and future directions Effect of genetic variants, especially CYP2C9 and VKORC1, on the pharmacology of warfarin Extracting research-quality phenotypes from electronic health records to support precision medicine Size matters: how population size influences genotype-phenotype association studies in anonymized data Biobanks and electronic medical records: enabling cost-effective research Secondary use of clinical data: the Vanderbilt approach Using linked data for mining drug-drug interactions in electronic health records Integrating EMR-linked and in vivo functional genetic data to identify new genotype-phenotype associations STRATEGIES FOR EQUITABLE PHARMACOGENOMIC-GUIDED WARFARIN DOSING AMONG EUROPEAN AND AFRICAN AMERICAN INDIVIDUALS IN A CLINICAL POPULATION Ethnicity-specific pharmacogenetics: the case of warfarin in African Americans Models of interinstitutional partnerships between research intensive universities and minority serving institutions (MSI) across the Clinical Translational Science Award (CTSA) consortium.Phenome-Wide Association Studies as a Tool to Advance Precision Medicine.A pharmacogenetics-based warfarin maintenance dosing algorithm from Northern Chinese patients.Genetic variant in folate homeostasis is associated with lower warfarin dose in African Americans.Enabling genomic-phenomic association discovery without sacrificing anonymity.Poor warfarin dose prediction with pharmacogenetic algorithms that exclude genotypes important for African Americans.Genotype and risk of major bleeding during warfarin treatment.Extracting Primary Open-Angle Glaucoma from Electronic Medical Records for Genetic Association Studies Race influences warfarin dose changes associated with genetic factors.The success of pharmacogenomics in moving genetic association studies from bench to bedside: study design and implementation of precision medicine in the post-GWAS era.Desiderata for computable representations of electronic health records-driven phenotype algorithms.Development of phenotype algorithms using electronic medical records and incorporating natural language processing.Cardiovascular pharmacogenomics: the future of cardiovascular therapeutics?Integrating electronic health record genotype and phenotype datasets to transform patient care Pharmacogenomics of warfarin in populations of African descent.Effect of NQO1 and CYP4F2 genotypes on warfarin dose requirements in Hispanic-Americans and African-Americans.Scientific challenges and implementation barriers to translation of pharmacogenomics in clinical practice.Does CALU SNP rs1043550 contribute variability to therapeutic warfarin dosing requirements?Comparative evaluation of warfarin utilisation in two primary healthcare clinics in the Cape Town area Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.Electronic medical records as a tool in clinical pharmacology: opportunities and challenges.Opportunities for genomic clinical decision support interventions.Electronic health record design and implementation for pharmacogenomics: a local perspective.Racial susceptibility for QT prolongation in acute drug overdoses.Clinically actionable genotypes among 10,000 patients with preemptive pharmacogenomic testing Genetic determinants of response to cardiovascular drugs.Warfarin Pharmacogenomics in Diverse Populations.Novel regulatory variant detected on the VKORC1 haplotype that is associated with warfarin dose.

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Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record.

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P2860

CYP2C9*8 is prevalent among African-Americans: implications for pharmacogenetic dosing

PLINK: a tool set for whole-genome association and population-based linkage analyses

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

Dabigatran versus warfarin in patients with atrial fibrillation

Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups

A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose

Estimation of the warfarin dose with clinical and pharmacogenetic data.

Finding unique filter sets in PLATO: a precursor to efficient interaction analysis in GWAS data.

10 years of oral anticoagulant pharmacogenomics: what difference will it make? A critical appraisal.

Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record.

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