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Age-related decrease of meiotic cohesins in human oocytesOocyte Maturation and DevelopmentOocyte development, meiosis and aneuploidySister chromatid segregation in meiosis II: deprotection through phosphorylationMeikin is a conserved regulator of meiosis-I-specific kinetochore functionPremature dyad separation in meiosis II is the major segregation error with maternal age in mouse oocytesBivalent separation into univalents precedes age-related meiosis I errors in oocytes.PP2A regulates kinetochore-microtubule attachment during meiosis I in oocyte.Age-related increase in aneuploidy and alteration of gene expression in mouse first polar bodiesRNA-binding proteins in human oogenesis: Balancing differentiation and self-renewal in the female fetal germlineReduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged mice.Divergent kleisin subunits of cohesin specify mechanisms to tether and release meiotic chromosomes.Meiotic cohesin STAG3 is required for chromosome axis formation and sister chromatid cohesionIdentification of chromosomal errors in human preimplantation embryos with oligonucleotide DNA microarray.Oocyte ageing and epigenetics.Mouse oocytes depend on BubR1 for proper chromosome segregation but not for prophase I arrestMaternal Germinal Trisomy 21 in Down SyndromeNew evidence that SAC can tolerate misaligned chromosomes in mouse oocytes.Chromosome cohesion decreases in human eggs with advanced maternal age.Cohesin-interacting protein WAPL-1 regulates meiotic chromosome structure and cohesion by antagonizing specific cohesin complexes.Unique geometry of sister kinetochores in human oocytes during meiosis I may explain maternal age-associated increases in chromosomal abnormalities.Evidence for cohesin sliding along budding yeast chromosomes.Dynamic and Stable Cohesins Regulate Synaptonemal Complex Assembly and Chromosome Segregation.C-phycocyanin protects against low fertility by inhibiting reactive oxygen species in aging mice.Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments.The association between the oocyte pool and aneuploidy: a comparative study of the reproductive potential of young and aged mice.Meiotic Recombination: The Essence of Heredity.Age-Related Loss of Cohesion: Causes and Effects.Decrease in expression of maternal effect gene Mater is associated with maternal ageing in mice.Elevated intracellular pH appears in aged oocytes and causes oocyte aneuploidy associated with the loss of cohesion in mice.Reduced chromosome cohesion measured by interkinetochore distance is associated with aneuploidy even in oocytes from young mice.Human female meiosis revised: new insights into the mechanisms of chromosome segregation and aneuploidies from advanced genomics and time-lapse imaging.Meiotic Divisions: No Place for Gender Equality.Inefficient Crossover Maturation Underlies Elevated Aneuploidy in Human Female Meiosis.Merotelic kinetochore attachment in oocyte meiosis II causes sister chromatids segregation errors in aged mice.Multiple Duties for Spindle Assembly Checkpoint Kinases in Meiosis.Double trouble in human aneuploidy.Germline mosaicism does not explain the maternal age effect on trisomy.Allele-specific methylation of imprinted genes in fetal cord blood is influenced by cis-acting genetic variants and parental factors
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Age-related aneuploidy through cohesion exhaustion.
@ast
Age-related aneuploidy through cohesion exhaustion.
@en
type
label
Age-related aneuploidy through cohesion exhaustion.
@ast
Age-related aneuploidy through cohesion exhaustion.
@en
prefLabel
Age-related aneuploidy through cohesion exhaustion.
@ast
Age-related aneuploidy through cohesion exhaustion.
@en
P2860
P356
P1433
P1476
Age-related aneuploidy through cohesion exhaustion.
@en
P2093
Rolf Jessberger
P2860
P304
P356
10.1038/EMBOR.2012.54
P577
2012-06-01T00:00:00Z