Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model - Test2 - elhamkhani - TriplyDB

Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model

Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model

http://www.wikidata.org/entity/Q36018639

about

Clinical development of gene therapy: results and lessons from recent successes Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism.Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors.Comparative Study of Liver Gene Transfer With AAV Vectors Based on Natural and Engineered AAV Capsids.Superior In vivo Transduction of Human Hepatocytes Using Engineered AAV3 Capsid.A lipidomics study reveals hepatic lipid signatures associating with deficiency of the LDL receptor in a rat model.Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells.CRISPR/Cas9: at the cutting edge of hepatology.Humanized mice: A brief overview on their diverse applications in biomedical research.Analysis of Hepatitis C Virus Particle Heterogeneity in Immunodeficient Human Liver Chimeric fah-/- Mice.Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease.Selecting the Best AAV Capsid for Human Studies.A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia.

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P2860

Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model

http://www.wikidata.org/entity/Q36018639

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model

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Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model

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Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model

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Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model

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prefLabel

Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model

@ast

Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model

@en

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Nature Communications

P1476

Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model

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Beatrice Bissig-Choisat

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Claudia Kettlun Leyton

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Francis P Pankowicz

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Hon-Chiu Eastwood Leung

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John A Goss

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Karl-Dimiter Bissig

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Lawrence Chan

http://www.w3.org/2001/XMLSchema#string

Leon Chen

http://www.w3.org/2001/XMLSchema#string

Mercedes Barzi

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Peter Bell

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P2860

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Biological, clinical and population relevance of 95 loci for blood lipids

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment

Molecular genetics of the LDL receptor gene in familial hypercholesterolemia

Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

Preparation of isolated rat liver cells

Hepatitis C virus replication in mice with chimeric human livers

Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.

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7339

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scholarly article

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10.1038/NCOMMS8339

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6

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William R. Lagor

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2015-06-17T00:00:00Z

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278677193

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26081744

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hypercholesterolemia

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4557302

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