Searching for new chemotherapies for tropical diseases: ruthenium-clotrimazole complexes display high in vitro activity against Leishmania major and Trypanosoma cruzi and low toxicity toward normal mammalian cells.
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Recent developments in drug discovery for leishmaniasis and human African trypanosomiasisNitro/nitrosyl-ruthenium complexes are potent and selective anti-Trypanosoma cruzi agents causing autophagy and necrotic parasite deathEvaluation of α,β-unsaturated ketones as antileishmanial agents.Antiplasmodial activity of iron(II) and ruthenium(II) organometallic complexes against Plasmodium falciparum blood parasites.A novel class of piperidones exhibit potent, selective and pro-apoptotic anti-leukemia properties.Metal-drug synergy: new ruthenium(II) complexes of ketoconazole are highly active against Leishmania major and Trypanosoma cruzi and nontoxic to human or murine normal cellsToward organometallic antischistosomal drug candidates.Organometallic gold(iii) complexes with hybrid SNS-donating thiosemicarbazone ligands: cytotoxicity and anti-Trypanosoma cruzi activity.Analysis of the cytotoxic effects of ruthenium-ketoconazole and ruthenium-clotrimazole complexes on cancer cells.Ruthenium-Clotrimazole complex has significant efficacy in the murine model of cutaneous leishmaniasis.Novel arylalkylamine compounds exhibits potent selective antiparasitic activity against Leishmania major.Spectroscopic Study of the Interactions of Ruthenium-Ketoconazole Complexes of Known Antiparasitic Activity with Human Serum Albumin and Apotransferrin.[(η(6)-Praziquantel)Cr(CO)3] derivatives with remarkable in vitro anti-schistosomal activity.Organometallic Derivatization of the Nematocidal Drug Monepantel Leads to Promising Antiparasitic Drug Candidates.DMSO-mediated ligand dissociation: renaissance for biological activity of N-heterocyclic-[Ru(η6-arene)Cl2] drug candidates.Characterization of the Activities of Dinuclear Thiolato-Bridged Arene Ruthenium Complexes against Toxoplasma gondii.Glycosylated metal chelators as anti-parasitic agents with tunable selectivity.A new ruthenium cyclopentadienyl azole compound with activity on tumor cell lines and trypanosomatid parasites
P2860
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P2860
Searching for new chemotherapies for tropical diseases: ruthenium-clotrimazole complexes display high in vitro activity against Leishmania major and Trypanosoma cruzi and low toxicity toward normal mammalian cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Searching for new chemotherapi ...... toward normal mammalian cells.
@ast
Searching for new chemotherapi ...... toward normal mammalian cells.
@en
type
label
Searching for new chemotherapi ...... toward normal mammalian cells.
@ast
Searching for new chemotherapi ...... toward normal mammalian cells.
@en
prefLabel
Searching for new chemotherapi ...... toward normal mammalian cells.
@ast
Searching for new chemotherapi ...... toward normal mammalian cells.
@en
P2093
P2860
P356
P1476
Searching for new chemotherapi ...... toward normal mammalian cells.
@en
P2093
Aaron Sattler
Alberto Martínez
Antonio Sánchez
Eva Iniguez
Linda Herrera
Marina Tyan
Roberto A Sánchez-Delgado
Rosa A Maldonado
Teresia Carreon
P2860
P304
P356
10.1021/JM300070H
P407
P577
2012-04-09T00:00:00Z