Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide
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Rho GTPases: Novel Players in the Regulation of the DNA Damage Response?Cardiac risk in the treatment of breast cancer: assessment and management.Inhibition of cell growth and VEGF expression in ovarian cancer cells by flavonoidsChemotherapy-Induced Cardiotoxicity: Pathophysiology and PreventionCancer therapy-induced cardiotoxicity: basic mechanisms and potential cardioprotective therapies.Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevanceDifferential effects of lovastatin on cisplatin responses in normal human mesothelial cells versus cancer cells: implication for therapy.Lovastatin prevents bleomycin-induced DNA damage to HepG2 cells.Rac1 modulates acute and subacute genotoxin-induced hepatic stress responses, fibrosis and liver agingStatins are logical candidates for overcoming limitations of targeting therapies on malignancy: their potential application to gastrointestinal cancers.Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity.Rho inhibition by lovastatin affects apoptosis and DSB repair of primary human lung cells in vitro and lung tissue in vivo following fractionated irradiationRac1-mediated cardiac damage causes diastolic dysfunction in a mouse model of subacute doxorubicin-induced cardiotoxicity.Concepts in cardio-oncology: definitions, mechanisms, diagnosis and treatment strategies of cancer therapy-induced cardiotoxicity.Principles of a risk evaluation and mitigation strategy (REMS) for breast cancer patients receiving potentially cardiotoxic adjuvant treatments.Statins in anthracycline-induced cardiotoxicity: Rac and Rho, and the heartbreakers.Rac1 protein signaling is required for DNA damage response stimulated by topoisomerase II poisons.Modulation of anthracycline-induced cytotoxicity by targeting the prenylated proteome in myeloid leukemia cells.Lovastatin enhances the genotoxicity of doxorubicin in Chinese hamster V79 cells via noncovalent DNA binding.Doxorubicin upregulates CXCR4 via miR-200c/ZEB1-dependent mechanism in human cardiac mesenchymal progenitor cells.Atorvastatin Downregulates In Vitro Methyl Methanesulfonate and Cyclophosphamide Alkylation-Mediated Cellular and DNA Injuries.
P2860
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P2860
Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide
description
2006 nî lūn-bûn
@nan
2006年の論文
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2006年学术文章
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2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
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2006年學術文章
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2006年學術文章
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name
Lovastatin protects human endo ...... rugs doxorubicin and etoposide
@ast
Lovastatin protects human endo ...... rugs doxorubicin and etoposide
@en
type
label
Lovastatin protects human endo ...... rugs doxorubicin and etoposide
@ast
Lovastatin protects human endo ...... rugs doxorubicin and etoposide
@en
prefLabel
Lovastatin protects human endo ...... rugs doxorubicin and etoposide
@ast
Lovastatin protects human endo ...... rugs doxorubicin and etoposide
@en
P2093
P2860
P356
P1476
Lovastatin protects human endo ...... rugs doxorubicin and etoposide
@en
P2093
P2860
P304
P356
10.1038/SJ.BJP.0706953
P407
P577
2006-11-06T00:00:00Z