Microtubules regulate GEF-H1 in response to extracellular matrix stiffness. - Test2 - elhamkhani - TriplyDB

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness.

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness.

http://www.wikidata.org/entity/Q36066653

about

Focal adhesions, stress fibers and mechanical tension At the leading edge of three-dimensional cell migration From mechanical force to RhoA activation Central role of the exchange factor GEF-H1 in TNF-α-induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells.TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion.RalB regulates contractility-driven cancer dissemination upon TGFβ stimulation via the RhoGEF GEF-H1 Paxillin mediates stretch-induced Rho signaling and endothelial permeability via assembly of paxillin-p42/44MAPK-GEF-H1 complex.3D collagen alignment limits protrusions to enhance breast cancer cell persistence.Stiffness-activated GEF-H1 expression exacerbates LPS-induced lung inflammation Rho GEFs and GAPs: emerging integrators of extracellular matrix signaling Fibroblasts Lead the Way: A Unified View of 3D Cell Motility A direct interaction between fascin and microtubules contributes to adhesion dynamics and cell migration.The tension mounts: stress fibers as force-generating mechanotransducers Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton.Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches.Breast tumor and stromal cell responses to TGF-β and hypoxia in matrix deposition.RhoA is down-regulated at cell-cell contacts via p190RhoGAP-B in response to tensional homeostasis.Control of myofibroblast differentiation by microtubule dynamics through a regulated localization of mDia2 Silica-based branched hollow microfibers as a biomimetic extracellular matrix for promoting tumor cell growth in vitro and in vivo.Regulation of cell adhesion and migration by cell-derived matrices.GEF-H1 is necessary for neutrophil shear stress-induced migration during inflammation.Physiological ranges of matrix rigidity modulate primary mouse hepatocyte function in part through hepatocyte nuclear factor 4 alpha.Rho family GTPases: making it to the third dimension.I'm coming to GEF you: Regulation of RhoGEFs during cell migration.Colchicine modulates calcium homeostasis and electrical property of HL-1 cells.Single and collective cell migration: the mechanics of adhesions.Neutrophil mechanotransduction: A GEF to sense fluid shear stress.Guanine nucleotide exchange factor H1 can be a new biomarker of melanoma.Extracellular matrix stiffness and cell contractility control RNA localization to promote cell migration.Mesenchymal Cell Invasion Requires Cooperative Regulation of Persistent Microtubule Growth by SLAIN2 and CLASP1.A Rho signaling network links microtubules to PKD controlled carrier transport to focal adhesions

P2860

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P2860

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness.

http://www.wikidata.org/entity/Q36066653

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

@zh-hk

2012年論文

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2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness.

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Microtubules regulate GEF-H1 in response to extracellular matrix stiffness.

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type

label

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness.

@ast

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness.

@en

prefLabel

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness.

@ast

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness.

@en

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MBC.E11-10-0876

P1433

Molecular Biology of the Cell

P1476

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness.

@en

P2093

Carolyn A Pehlke

http://www.w3.org/2001/XMLSchema#string

David R Inman

http://www.w3.org/2001/XMLSchema#string

Jessica N Heck

http://www.w3.org/2001/XMLSchema#string

Maria G Garcia-Mendoza

http://www.w3.org/2001/XMLSchema#string

Patricia J Keely

http://www.w3.org/2001/XMLSchema#string

P2860

Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases

Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton

p21-activated kinase 1 phosphorylates and regulates 14-3-3 binding to GEF-H1, a microtubule-localized Rho exchange factor

Paracingulin regulates the activity of Rac1 and RhoA GTPases by recruiting Tiam1 and GEF-H1 to epithelial junctions

Use of three-dimensional collagen gels to study mechanotransduction in T47D breast epithelial cells

Greatly increased occurrence of breast cancers in areas of mammographically dense tissue

PAK4 mediates morphological changes through the regulation of GEF-H1

Binding of GEF-H1 to the tight junction-associated adaptor cingulin results in inhibition of Rho signaling and G1/S phase transition

Calpain-6, a microtubule-stabilizing protein, regulates Rac1 activity and cell motility through interaction with GEF-H1

Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration.

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2583-2592

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scholarly article

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10.1091/MBC.E11-10-0876

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13

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23

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Suzanne M Ponik

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2012-05-16T00:00:00Z

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P5875

224972428

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P698

22593214

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P921

extracellular matrix

P932

3386221

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