An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes.
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Ubiquitin-dependent regulation of Foxp3 and Treg functionTreg functional stability and its responsiveness to the microenvironmentHypoxia-inducible factors regulate T cell metabolism and functionVagaries of fluorochrome reporter gene expression in Foxp3+ regulatory T cells.Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responsesUbiquitous points of control over regulatory T cells.Rapid rebound of the Treg compartment in DEREG mice limits the impact of Treg depletion on mycobacterial burden, but prevents autoimmunityPD-1 regulates extrathymic regulatory T-cell differentiation.Master regulators or lineage-specifying? Changing views on CD4+ T cell transcription factorsDefining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouseModification of the FoxP3 transcription factor principally affects inducible T regulatory cells in a model of experimental autoimmune encephalomyelitis.miR-182 and miR-10a are key regulators of Treg specialisation and stability during Schistosome and Leishmania-associated inflammationHIF transcription factors, inflammation, and immunity.Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo.The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.Retina-specific T regulatory cells bring about resolution and maintain remission of autoimmune uveitis.HY-Specific Induced Regulatory T Cells Display High Specificity and Efficacy in the Prevention of Acute Graft-versus-Host DiseasePim-2 Kinase Influences Regulatory T Cell Function and Stability by Mediating Foxp3 Protein N-terminal PhosphorylationTreg cells, life history, and diversityTranscription factor Foxp3 and its protein partners form a complex regulatory network.Foxp3 expression is required for the induction of therapeutic tissue toleranceHypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosaMolecular and biological role of the FOXP3 N-terminal domain in immune regulation by T regulatory/suppressor cellsAntigen- and cytokine-driven accumulation of regulatory T cells in visceral adipose tissue of lean miceAn obligate cell-intrinsic function for CD28 in TregsPlasticity within the αβ⁺CD4⁺ T-cell lineage: when, how and what for?Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery.Generation and function of induced regulatory T cells.Tumour suppressor death-associated protein kinase targets cytoplasmic HIF-1α for Th17 suppression.MicroRNA-17 Modulates Regulatory T Cell Function by Targeting Co-regulators of the Foxp3 Transcription FactorNonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model.Differential splicing across immune system lineagesCCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsetsDifferential response of regulatory and conventional CD4⁺ lymphocytes to CD3 engagement: clues to a possible mechanism of anti-CD3 action?Interindividual variation in human T regulatory cells.Fat-resident Tregs: an emerging guard protecting from obesity-associated metabolic disorders.Regulatory T cells in nonlymphoid tissues.Searching for the Achilles Heel of FOXP3Extra-thymically induced T regulatory cell subsets: the optimal target for antigen-specific immunotherapy.Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity.
P2860
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P2860
An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
An N-terminal mutation of the ...... itis but exacerbates diabetes.
@ast
An N-terminal mutation of the ...... itis but exacerbates diabetes.
@en
type
label
An N-terminal mutation of the ...... itis but exacerbates diabetes.
@ast
An N-terminal mutation of the ...... itis but exacerbates diabetes.
@en
prefLabel
An N-terminal mutation of the ...... itis but exacerbates diabetes.
@ast
An N-terminal mutation of the ...... itis but exacerbates diabetes.
@en
P2093
P2860
P1433
P1476
An N-terminal mutation of the ...... itis but exacerbates diabetes.
@en
P2093
Alexander Y Rudensky
Christophe Benoist
Daniela Cipolletta
Diane Mathis
Dipayan Rudra
Jaime Darce
Junko Nishio
P2860
P304
P356
10.1016/J.IMMUNI.2012.04.007
P407
P577
2012-05-10T00:00:00Z