GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin
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Paxillin comes of agePhosphorylation of tyrosine 285 of PAK1 facilitates βPIX/GIT1 binding and adhesion turnoverGIT1 Paxillin-binding Domain Is a Four-helix Bundle, and It Binds to Both Paxillin LD2 and LD4 MotifsStructural Analysis of the Interactions Between Paxillin LD Motifs and α-ParvinMolecular Recognition of Leucine-Aspartate Repeat (LD) Motifs by the Focal Adhesion Targeting Homology Domain of Cerebral Cavernous Malformation 3 (CCM3)Biochemical and functional characterization of the interaction between liprin-α1 and GIT1: implications for the regulation of cell motilityConsensus substrate sequence for protein-tyrosine phosphatase receptor type ZMyosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation.Identification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons.Identification of two tyrosine residues required for the intramolecular mechanism implicated in GIT1 activation.G-protein-coupled receptor kinase interactor-1 (GIT1) is a new endothelial nitric-oxide synthase (eNOS) interactor with functional effects on vascular homeostasis.Impaired fear response in mice lacking GIT1.The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events.Endothelial nitric-oxide synthase (eNOS) is activated through G-protein-coupled receptor kinase-interacting protein 1 (GIT1) tyrosine phosphorylation and Src proteinMicroRNA-149 targets GIT1 to suppress integrin signaling and breast cancer metastasisAllosteric regulation of focal adhesion kinase by PIP₂ and ATP.Specific dephosphorylation at tyr-554 of git1 by ptprz promotes its association with paxillin and hic-5.How focal adhesion kinase achieves regulation by linking ligand binding, localization and actionGIT1 is a novel prognostic biomarker and facilitates tumor progression via activating ERK/MMP9 signaling in hepatocellular carcinomaNuclear transport of paxillin depends on focal adhesion dynamics and FAT domainsThe PIX-GIT complex: a G protein signaling cassette in control of cell shapeMicroRNA-34c Suppresses Breast Cancer Migration and Invasion by Targeting GIT1.How to find a leucine in a haystack? Structure, ligand recognition and regulation of leucine-aspartic acid (LD) motifs.MiR-138 inhibits cell proliferation and reverses epithelial-mesenchymal transition in non-small cell lung cancer cells by targeting GIT1 and SEMA4CThe adaptor protein and Arf GTPase-activating protein Cat-1/Git-1 is required for cellular transformation.miR-149 in Human Cancer: A Systemic Review.Differential expression of the ARF GAP genes GIT1 and GIT2 in mouse tissues.ITGA2B and ITGA8 are predictive of prognosis in clear cell renal cell carcinoma patients.Spatial intratumoural heterogeneity in the expression of GIT1 is associated with poor prognostic outcome in oestrogen receptor positive breast cancer patients with synchronous lymph node metastases.
P2860
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P2860
GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin
@ast
GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin
@en
type
label
GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin
@ast
GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin
@en
prefLabel
GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin
@ast
GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin
@en
P2093
P2860
P50
P1433
P1476
GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin
@en
P2093
Collin E Davidson
J Tyler Roseman
Robert Schmalzigaug
Yanghui Xing
P2860
P304
P356
10.1016/J.CELLSIG.2007.03.010
P577
2007-03-30T00:00:00Z