about
Targeting the RAS oncogene.RSK phosphorylates SOS1 creating 14-3-3-docking sites and negatively regulating MAPK activationDysregulation of cell polarity proteins synergize with oncogenes or the microenvironment to induce invasive behavior in epithelial cellsActivated Ras alters lens and corneal development through induction of distinct downstream targets.Cancer gene discovery in hepatocellular carcinomaPersistent ERK/MAPK activation promotes lactotrope differentiation and diminishes tumorigenic phenotype.An Update on the Biology of RAS/RAF Mutations in Colorectal Cancer.Molecular characterization of apoptosis induced by CARF silencing in human cancer cellsNF-κB and cancer: a paradigm of Yin-Yang.Environmental contaminants: Is male reproductive health at risk?Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells.Activated mutant NRas(Q61K) drives aberrant melanocyte signaling, survival, and invasiveness via a Rac1-dependent mechanism.Identification of novel vascular projections with cellular trafficking abilities on the microvasculature of pancreatic ductal adenocarcinoma.Screening pancreatic oncogenes in zebrafish using the Gal4/UAS system.C-Raf is required for the initiation of lung cancer by K-Ras(G12D).Differential regulation of N-Myc and c-Myc synthesis, degradation, and transcriptional activity by the Ras/mitogen-activated protein kinase pathway.Phosphorylation of Mps1 by BRAFV600E prevents Mps1 degradation and contributes to chromosome instability in melanoma.Frequent loss of RAF kinase inhibitor protein expression in acute myeloid leukemia.The involvement of MCT-1 oncoprotein in inducing mitotic catastrophe and nuclear abnormalities.Notch and Kras in pancreatic cancer: at the crossroads of mutation, differentiation and signaling.Inhibition of extracellular signal-regulated kinase 1 by adenovirus mediated small interfering RNA attenuates hepatic fibrosis in rats.Oncogenic K-ras "addiction" and synthetic lethality.Crosstalk of Ras and Rho: activation of RhoA abates Kras-induced liver tumorigenesis in transgenic zebrafish models.Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Modelling oncogenic Ras/Raf signalling in the mouse.
@ast
Modelling oncogenic Ras/Raf signalling in the mouse.
@en
type
label
Modelling oncogenic Ras/Raf signalling in the mouse.
@ast
Modelling oncogenic Ras/Raf signalling in the mouse.
@en
prefLabel
Modelling oncogenic Ras/Raf signalling in the mouse.
@ast
Modelling oncogenic Ras/Raf signalling in the mouse.
@en
P2860
P1476
Modelling oncogenic Ras/Raf signalling in the mouse.
@en
P2093
Florian A Karreth
P2860
P356
10.1016/J.GDE.2008.12.006
P577
2009-02-07T00:00:00Z