Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.
about
Alternatives to currently used antimalarial drugs: in search of a magic bulletMacrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum.Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.Production and characterization of specific monoclonal antibodies binding the Plasmodium falciparum diagnostic biomarker, histidine-rich protein 2Valproic acid as a potential inhibitor of Plasmodium falciparum histone deacetylase 1 (PfHDAC1): an in silico approach.Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stagesA pantetheinase-resistant pantothenamide with potent, on-target, and selective antiplasmodial activityA serine-arginine-rich (SR) splicing factor modulates alternative splicing of over a thousand genes in Toxoplasma gondii.Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasitesDesign and Synthesis of Novel Anti-Plasmodial Histone Deacetylase Inhibitors Containing an Alkoxyamide Connecting Unit.Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACsEffect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth.Antiplasmodial drug targets: a patent review (2000 - 2013).Transcriptional Profiling Defines Histone Acetylation as a Regulator of Gene Expression during Human-to-Mosquito Transmission of the Malaria Parasite Plasmodium falciparum.Synthesis, antimalarial properties, and SAR studies of alkoxyurea-based HDAC inhibitors.Design and Synthesis of Terephthalic Acid-Based Histone Deacetylase Inhibitors with Dual-Stage Anti-Plasmodium Activity.Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity† †The authors declare no competing interests. ‡ ‡Electronic supplementary information (ESI) available: SuppleHistone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity.Improper protein trafficking contributes to artemisinin sensitivity in cells lacking the KDAC Rpd3p.Cancer and parasitic infections: similarities and opportunities for the development of new control tools
P2860
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P2860
Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.
@ast
Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.
@en
type
label
Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.
@ast
Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.
@en
prefLabel
Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.
@ast
Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.
@en
P2093
P2860
P50
P356
P1476
Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.
@en
P2093
Christopher D Goodman
Katherine T Andrews
Subathdrage D M Sumanadasa
Tram Anh Do
P2860
P304
P356
10.1128/AAC.00030-12
P407
P50
P577
2012-04-16T00:00:00Z