Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia - Test2 - elhamkhani - TriplyDB

Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia

Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia

http://www.wikidata.org/entity/Q36097274

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A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP Cytosolic Innate Immune Sensing and Signaling upon Infection Cyclic di-GMP: the first 25 years of a universal bacterial second messenger Rationale, progress and development of vaccines utilizing STING-activating cyclic dinucleotide adjuvants Species-specific detection of the antiviral small-molecule compound CMA by STING Structure of a diguanylate cyclase from Thermotoga maritima: insights into activation, feedback inhibition and thermostability Inducible bronchus-associated lymphoid tissue elicited by a protein cage nanoparticle enhances protection in mice against diverse respiratory viruses.In Vivo Synthesis of Cyclic-di-GMP Using a Recombinant Adenovirus Preferentially Improves Adaptive Immune Responses against Extracellular Antigens.Small protein-mediated quorum sensing in a Gram-negative bacterium.c-di-GMP enhances protective innate immunity in a murine model of pertussis Comparative effects of carbapenems on bacterial load and host immune response in a Klebsiella pneumoniae murine pneumonia model.STING ligand c-di-GMP improves cancer vaccination against metastatic breast cancer The mucosal adjuvant cyclic di-AMP exerts immune stimulatory effects on dendritic cells and macrophages Functional Genomic Screen Identifies Klebsiella pneumoniae Factors Implicated in Blocking Nuclear Factor κB (NF-κB) Signaling Inducible innate resistance of lung epithelium to infection.Innate Immune Signaling Activated by MDR Bacteria in the Airway Stimulation of lung innate immunity protects against lethal pneumococcal pneumonia in mice c-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection.Modeling Klebsiella pneumoniae pathogenesis by infection of the wax moth Galleria mellonella.The bacterial second messenger c-di-GMP: mechanisms of signalling.Cyclic di-nucleotides: new era for small molecules as adjuvants.Sensing the messenger: the diverse ways that bacteria signal through c-di-GMP.Biofilm infections, their resilience to therapy and innovative treatment strategies.Adjuvant immunotherapies as a novel approach to bacterial infections.Intranasal formulations: promising strategy to deliver vaccines.OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids.Thiophosphate analogs of c-di-GMP: impact on polymorphism.Large-scale production of the immunomodulator c-di-GMP from GMP and ATP by an enzymatic cascade.Cyclic Dinucleotides in the Scope of the Mammalian Immune System.Stimulation of innate immunity by in vivo cyclic di-GMP synthesis using adenovirus.Zinc supplementation restores PU.1 and Nrf2 nuclear binding in alveolar macrophages and improves redox balance and bacterial clearance in the lungs of alcohol-fed rats.Enzymatic Production of c-di-GMP Using a Thermophilic Diguanylate Cyclase.Design and synthesis of bis-carbamate analogs of cyclic bis-(3'-5')-diguanylic acid (c-di-GMP) and the acyclic dimer PGPG.High Levels of Cyclic Di-GMP in Klebsiella pneumoniae Attenuate Virulence in the Lung.STING-Activating Adjuvants Elicit a Th17 Immune Response and Protect against Mycobacterium tuberculosis Infection.Immunostimulation with macrophage-activating lipopeptide-2 increased survival in murine pneumonia.Enhanced immunostimulatory activity of cyclic dinucleotides on mouse cells when complexed with a cell-penetrating peptide or combined with CpG.MPYS/STING-mediated TNF-α, not type I IFN, is essential for the mucosal adjuvant activity of (3'-5')-cyclic-di-guanosine-monophosphate in vivo.Mechanism-Based Disease Progression Model Describing Host-Pathogen Interactions During the Pathogenesis of Acinetobacter baumannii Pneumonia

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P2860

Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia

http://www.wikidata.org/entity/Q36097274

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Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia

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Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia

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Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia

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Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia

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Infection and Immunity

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Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia

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P2093

David K R Karaolis

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Hallie Liang

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Michael W Newstead

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Theodore J Standiford

http://www.w3.org/2001/XMLSchema#string

Urvhashi Bhan

http://www.w3.org/2001/XMLSchema#string

Xianying Zeng

http://www.w3.org/2001/XMLSchema#string

Yoshihiro Hayakawa

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of a novel response regulator required for the swarmer-to-stalked-cell transition in Caulobacter crescentus

Dendritic cells and the control of immunity

Interferon-inducible protein 10, monokine induced by interferon gamma, and interferon-inducible T-cell alpha chemoattractant are produced by thymic epithelial cells and attract T-cell receptor (TCR) alphabeta+ CD8+ single-positive T cells, TCRgammad

Autolysis and autoaggregation in Pseudomonas aeruginosa colony morphology mutants

Novel domains of the prokaryotic two-component signal transduction systems

Regulation of cellulose synthesis in Acetobacter xylinum by cyclic diguanylic acid

CXC chemokine receptor CXCR2 is essential for protective innate host response in murine Pseudomonas aeruginosa pneumonia.

In vivo regulation of replicative Legionella pneumophila lung infection by endogenous interleukin-12.

c-di-GMP (3'-5'-cyclic diguanylic acid) inhibits Staphylococcus aureus cell-cell interactions and biofilm formation

3',5'-cyclic diguanylic acid reduces the virulence of biofilm-forming Staphylococcus aureus strains in a mouse model of mastitis infection.

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17646358

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