Cell signaling pathways as control modules: complexity for simplicity?
about
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networksRetroactivity in the Context of Modularly Structured Biomolecular SystemsA Compartmentalized Out-of-Equilibrium Enzymatic Reaction Network for Sustained Autonomous Movement.Rethinking gene regulatory networks in light of alternative splicing, intrinsically disordered protein domains, and post-translational modificationsThreshold-dominated regulation hides genetic variation in gene expression networksSystem theoretical investigation of human epidermal growth factor receptor-mediated signalling.Reverse engineering of bacterial chemotaxis pathway via frequency domain analysis.Global network analysis of phenotypic effects: protein networks and toxicity modulation in Saccharomyces cerevisiae.Paradoxical results in perturbation-based signaling network reconstructionUnderstanding biology by reverse engineering the controlMutation, specialization, and hypersensitivity in highly optimized tolerance.Untangling the wires: a strategy to trace functional interactions in signaling and gene networks.The global transcriptional regulatory network for metabolism in Escherichia coli exhibits few dominant functional states.Reverse engineering biomolecular systems using -omic data: challenges, progress and opportunities.Positive feedback may cause the biphasic response observed in the chemoattractant-induced response of Dictyostelium cells.Adaptive control model reveals systematic feedback and key molecules in metabolic pathway regulation.Modular composition of gene transcription networks.Designer gene networks: Towards fundamental cellular control.Systems interface biology.Computational approaches for translational clinical research in disease progression.Hierarchical feedback modules and reaction hubs in cell signaling networks.Genomic approaches in dissecting complex biological pathways.A molecular model for intercellular synchronization in the mammalian circadian clock.The evolution of signaling complexity suggests a mechanism for reducing the genomic search space in human association studies.Reduced-order modelling of biochemical networks: application to the GTPase-cycle signalling moduleCancer cell growth and survival as a system-level property sustained by enhanced glycolysis and mitochondrial metabolic remodelingA mathematical tool for exploring the dynamics of biological networks.Synthetic multivalent ligands as probes of signal transductionModular cell biology: retroactivity and insulationQuantifying gene network connectivity in silico: scalability and accuracy of a modular approachThe energy costs of insulators in biochemical networksA Novel Malaria Pf/Pv Ab Rapid Diagnostic Test Using a Differential Diagnostic Marker Identified by Network Biology.Systems level modeling of the cell cycle using budding yeast.Communication shapes sensory response in multicellular networksMixed-integer nonlinear optimisation approach to coarse-graining biochemical networks.Robustness properties of circadian clock architectures.Computational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transductionBiological signalling activity measurements using mass spectrometry.Understanding complexity in neurodegenerative diseases: in silico reconstruction of emergence.Methods of Model Reduction for Large-Scale Biological Systems: A Survey of Current Methods and Trends.
P2860
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P2860
Cell signaling pathways as control modules: complexity for simplicity?
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Cell signaling pathways as control modules: complexity for simplicity?
@ast
Cell signaling pathways as control modules: complexity for simplicity?
@en
type
label
Cell signaling pathways as control modules: complexity for simplicity?
@ast
Cell signaling pathways as control modules: complexity for simplicity?
@en
prefLabel
Cell signaling pathways as control modules: complexity for simplicity?
@ast
Cell signaling pathways as control modules: complexity for simplicity?
@en
P2860
P356
P1476
Cell signaling pathways as control modules: complexity for simplicity?
@en
P2093
D A Lauffenburger
P2860
P304
P356
10.1073/PNAS.97.10.5031
P407
P577
2000-05-01T00:00:00Z