Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators.
about
Three rare diseases in one Sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith–Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivityGenetically encoding a light switch in an ionotropic glutamate receptor reveals subunit-specific interfaces.Context-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects.Emerging structural insights into the function of ionotropic glutamate receptors.A Novel Binding Mode Reveals Two Distinct Classes of NMDA Receptor GluN2B-selective AntagonistsAmino-terminal domain tetramer organization and structural effects of zinc binding in the N-methyl-D-aspartate (NMDA) receptor.Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains.Influence of GluN2 subunit identity on NMDA receptor function.Distinct functional and pharmacological properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA receptors.NMDA Receptors in the Central Nervous System.
P2860
Q27683955-9FA2C6BC-BBAB-48D2-AF6E-F1B6350CE9A7Q30361205-AAA0DF40-423D-4A6B-BB3B-6BEE5D5C7777Q35202428-23E559D7-4126-4DE8-8703-6F74576195EDQ35731584-DD717FE5-78F1-4B7F-A845-0140D49DDF01Q36879280-7B5D40A9-8526-44BD-AD97-A08AFF0BCAEDQ37311908-3F8F5EF5-D84B-41F2-A70C-BAD44EA2BF2EQ37480684-72DBAE56-813D-42E6-B9FF-4CB7C6FB1450Q38078685-D1EB3AF7-3066-43CF-A927-18BA0FA9B219Q38316913-304BA07D-5540-4E6D-96FC-C87397C0B5A2Q48029905-82DE0DB7-1D9F-4890-A10A-0D943F3D6A6B
P2860
Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
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name
Mapping the binding of GluN2B- ...... egative allosteric modulators.
@ast
Mapping the binding of GluN2B- ...... egative allosteric modulators.
@en
type
label
Mapping the binding of GluN2B- ...... egative allosteric modulators.
@ast
Mapping the binding of GluN2B- ...... egative allosteric modulators.
@en
prefLabel
Mapping the binding of GluN2B- ...... egative allosteric modulators.
@ast
Mapping the binding of GluN2B- ...... egative allosteric modulators.
@en
P2093
P2860
P356
P1476
Mapping the binding of GluN2B- ...... egative allosteric modulators.
@en
P2093
Dennis C Liotta
Erkan Karakas
Hiro Furukawa
Hongjie Yuan
James P Snyder
Matthew Geballe
Pieter B Burger
Stephen F Traynelis
P2860
P304
P356
10.1124/MOL.112.078568
P577
2012-05-17T00:00:00Z