Identification and validation of novel human pregnane X receptor activators among prescribed drugs via ligand-based virtual screening.
about
Modulation of xenobiotic receptors by steroidsOpen Source Bayesian Models. 1. Application to ADME/Tox and Drug Discovery DatasetsPathway analysis for drug repositioning based on public database miningBuilding a virtual ligand screening pipeline using free software: a surveyFusing dual-event data sets for Mycobacterium tuberculosis machine learning models and their evaluation.Thiazide-like diuretic drug metolazone activates human pregnane X receptor to induce cytochrome 3A4 and multidrug-resistance protein 1.Pharmacophore and 3D-QSAR characterization of 6-arylquinazolin-4-amines as Cdc2-like kinase 4 (Clk4) and dual specificity tyrosine-phosphorylation-regulated kinase 1A (Dyrk1A) inhibitorsDevelopment of time resolved fluorescence resonance energy transfer-based assay for FXR antagonist discoveryCombining computational methods for hit to lead optimization in Mycobacterium tuberculosis drug discovery.Quantitative high-throughput identification of drugs as modulators of human constitutive androstane receptor.Potent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease InhibitorsIdentification of novel activators of constitutive androstane receptor from FDA-approved drugs by integrated computational and biological approaches.Open Source Bayesian Models. 3. Composite Models for Prediction of Binned ResponsesPolypharmacy and food-drug interactions among older persons: a review.Activation of the constitutive androstane receptor inhibits gluconeogenesis without affecting lipogenesis or fatty acid synthesis in human hepatocytes.Predictive models for identifying the binding activity of structurally diverse chemicals to human pregnane X receptor.Involvement of CAR and PXR in the transcriptional regulation of CYP2B6 gene expression by ingredients from herbal medicines.Using TR-FRET to Investigate Protein-Protein Interactions: A Case Study of PXR-Coregulator Interaction.
P2860
Q27009230-9ECF1175-89C1-48F1-9023-64CE87BADF05Q28647980-731FA5AC-7BAC-4A8A-82E3-2FE52F3C48D2Q28657698-AB4CA13D-0690-4AC4-9B96-DD91BAC19338Q30044592-3A638791-F48D-415B-8E2B-883CF9F1029FQ30681280-47827AEA-E227-4870-BC1C-6BE49D650DF5Q34614106-70FD23FA-0072-4427-8E66-E0A93FE8A071Q34621349-F2CC4386-659B-4A3D-9BE9-AFD1BBBC0455Q34729209-EDEB9977-D769-46B5-9DC9-2FCDF4675449Q35019457-11CDEA71-7192-4406-B343-3147DD859751Q35627428-6034BB31-3D4A-4CFA-9B41-C83A1C861942Q36186145-87D3047C-2305-4DA7-AD04-8869A6226472Q36561847-E039D98E-FBB6-4B6C-A0D7-43FFD9160EFDQ36611267-0ADADE89-2529-4E20-9BAF-D79E18ED103CQ38060181-283482A6-015C-4EB5-9773-54851468BF8CQ38990036-6C94B269-CF73-43B7-8D7A-6844CCDC2EE6Q47933969-617488F8-3687-45DA-87BF-4BDF5C73DB7EQ50047208-D76B31A7-7B12-42FB-9F9C-FCBF659558EAQ50056522-DE371DE2-9E90-45BD-A8C4-E53D3CB50891
P2860
Identification and validation of novel human pregnane X receptor activators among prescribed drugs via ligand-based virtual screening.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Identification and validation ...... igand-based virtual screening.
@ast
Identification and validation ...... igand-based virtual screening.
@en
type
label
Identification and validation ...... igand-based virtual screening.
@ast
Identification and validation ...... igand-based virtual screening.
@en
prefLabel
Identification and validation ...... igand-based virtual screening.
@ast
Identification and validation ...... igand-based virtual screening.
@en
P2093
P2860
P356
P1476
Identification and validation ...... igand-based virtual screening.
@en
P2093
Gregory Kim
Hongbing Wang
Yongmei Pan
P2860
P304
P356
10.1124/DMD.110.035808
P577
2010-11-10T00:00:00Z