Fungal metabolite ophiobolin A as a promising anti-glioma agent: In vivo evaluation, structure-activity relationship and unique pyrrolylation of primary amines.
about
Cytoplasmic vacuolization in cell death and survivalOphiobolin A, a sesterpenoid fungal phytotoxin, displays different mechanisms of cell death in mammalian cells depending upon the cancer cell origin.The Biological Activities of Sesterterpenoid-Type Ophiobolins.Single dish gradient screening of small molecule localizationThe anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine.Sesterterpene ophiobolin biosynthesis involving multiple gene clusters in Aspergillus ustus.Ophiobolin A kills human glioblastoma cells by inducing endoplasmic reticulum stress via disruption of thiol proteostasis.The synthesis of cycloalka[b]furans via an Au(i)-catalyzed tandem reaction of 3-yne-1,2-diols.Influence of light on the biosynthesis of ophiobolin A by Bipolaris maydis.Covalent modification of biological targets with natural products through Paal-Knorr pyrrole formation.
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P2860
Fungal metabolite ophiobolin A as a promising anti-glioma agent: In vivo evaluation, structure-activity relationship and unique pyrrolylation of primary amines.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Fungal metabolite ophiobolin A ...... rrolylation of primary amines.
@ast
Fungal metabolite ophiobolin A ...... rrolylation of primary amines.
@en
type
label
Fungal metabolite ophiobolin A ...... rrolylation of primary amines.
@ast
Fungal metabolite ophiobolin A ...... rrolylation of primary amines.
@en
prefLabel
Fungal metabolite ophiobolin A ...... rrolylation of primary amines.
@ast
Fungal metabolite ophiobolin A ...... rrolylation of primary amines.
@en
P2093
P2860
P50
P1476
Fungal metabolite ophiobolin A ...... yrrolylation of primary amines
@en
P2093
Alexander Kornienko
Andrew J Brenner
John G Kuhn
Lance R English
Marlène Ferdérin
Ramesh Dasari
Robert Kiss
Romana Lisy
Steven T Whitten
Véronique Mathieu
P2860
P304
P356
10.1016/J.BMCL.2015.08.066
P407
P577
2015-08-24T00:00:00Z