Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?
about
Concordant and opposite roles of DNA-PK and the "facilitator of chromatin transcription" (FACT) in DNA repair, apoptosis and necrosis after cisplatinStructural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4DNA topoisomerase I inhibition by camptothecin induces escape of RNA polymerase II from promoter-proximal pause site, antisense transcription and histone acetylation at the human HIF-1alpha gene locus.Copper transporter 2 regulates the cellular accumulation and cytotoxicity of Cisplatin and Carboplatin.Tumour regression and ERCC1 nuclear protein expression predict clinical outcome in patients with gastro-oesophageal cancer treated with neoadjuvant chemotherapy.Recognition of platinum-DNA damage by poly(ADP-ribose) polymerase-1.Cellular responses to Cisplatin-induced DNA damage.Copper transporter 2 regulates endocytosis and controls tumor growth and sensitivity to cisplatin in vivo.Role of endonucleases XPF and XPG in nucleotide excision repair of platinated DNA and cisplatin/oxaliplatin cytotoxicity.Molecular mechanisms of resistance and toxicity associated with platinating agents.Identification of genetic variants contributing to cisplatin-induced cytotoxicity by use of a genomewide approachBis-picolinamide Ruthenium(III) Dihalide Complexes: Dichloride-to-Diiodide Exchange Generates Single trans Isomers with High Potency and Cancer Cell Selectivity.Modeling anticancer drug-DNA interactions via mixed QM/MM molecular dynamics simulations.Fucoxanthin enhances cisplatin-induced cytotoxicity via NFκB-mediated pathway and downregulates DNA repair gene expression in human hepatoma HepG2 cells.Germline genetic variations in drug action pathways predict clinical outcomes in advanced lung cancer treated with platinum-based chemotherapyEnhancement of cisplatin [cis-diammine dichloroplatinum (II)] cytotoxicity by O6-benzylguanine involves endoplasmic reticulum stress.Role of copper transporters in resistance to platinating agents.The use of X-ray absorption and synchrotron based micro-X-ray fluorescence spectroscopy to investigate anti-cancer metal compounds in vivo and in vitro.Fucoxanthin: a marine carotenoid exerting anti-cancer effects by affecting multiple mechanisms.Quercetin induces endoplasmic reticulum stress to enhance cDDP cytotoxicity in ovarian cancer: involvement of STAT3 signaling.Discrepancy between in vitro and in vivo antitumor effect of a new platinum(II) metallointercalator.Trans labilization of am(m)ine ligands from platinum(II) complexes by cancer cell extracts.Biological evaluation of transdichloridoplatinum(II) complexes with 3- and 4-acetylpyridine in comparison to cisplatin.Influence of the chloride concentration on ligand substitution reactions of [Pt(SMC)Cl(2)] with biologically relevant nucleophiles.Role of Protein Linked DNA Breaks in Cancer.Kinetic studies on the reactions of [Pd(dach)(X-Y)] complexes with some DNA constituents.Kinetic and mechanistic studies of 1,3-bis(2-pyridylimino)isoindolate Pt(II) derivatives. Experimental and new computational approach.Mass spectrometric analysis of ubiquitin–platinum interactions of leading anticancer drugs: MALDI versus ESI
P2860
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P2860
Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?
@ast
Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?
@en
type
label
Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?
@ast
Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?
@en
prefLabel
Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?
@ast
Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?
@en
P2860
P356
P1433
P1476
Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?
@en
P2093
Haralabos Zorbas
P2860
P304
P356
10.1002/CBIC.200400427
P577
2005-07-01T00:00:00Z