Cell culture-adaptive mutations promote viral protein-protein interactions and morphogenesis of infectious hepatitis C virus
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A CRISPR screen defines a signal peptide processing pathway required by flavivirusesGenetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine DesignGenetic characterization of hepatitis C virus in long-term RNA replication using Li23 cell culture systemsSingle strain isolation method for cell culture-adapted hepatitis C virus by end-point dilution and infection.hepatitis c Virus p7 is critical for capsid assembly and envelopmentInhibition of hepatitis C virus infection by DNA aptamer against NS2 protein.A Dual-reporter system for real-time monitoring and high-throughput CRISPR/Cas9 library screening of the hepatitis C virus.Production and characterization of high-titer serum-free cell culture grown hepatitis C virus particles of genotype 1-6.HCV induces the expression of Rubicon and UVRAG to temporally regulate the maturation of autophagosomes and viral replication.Detergent-resistant membrane association of NS2 and E2 during hepatitis C virus replicationTNF-α Induced by Hepatitis C Virus via TLR7 and TLR8 in Hepatocytes Supports Interferon Signaling via an Autocrine Mechanism.Adaptive Mutations Enhance Assembly and Cell-to-Cell Transmission of a High-Titer Hepatitis C Virus Genotype 5a Core-NS2 JFH1-Based Recombinant.A Library of Infectious Hepatitis C Viruses with Engineered Mutations in the E2 Gene Reveals Growth-Adaptive Mutations That Modulate Interactions with Scavenger Receptor Class B Type I.Transient activation of the PI3K-AKT pathway by hepatitis C virus to enhance viral entry.Hepatitis C Virus Resistance to Carbohydrate-Binding AgentsHepatitis C Virus-Induced Degradation of Cell Death-Inducing DFFA-Like Effector B Leads to Hepatic Lipid Dysregulation.Genetic and functional characterization of the N-terminal region of the hepatitis C virus NS2 proteinISG12a Restricts Hepatitis C Virus Infection through the Ubiquitination-Dependent Degradation Pathway.Characterization of hepatitis C virus intra- and intergenotypic chimeras reveals a role of the glycoproteins in virus envelopment.TIM-1 Promotes Hepatitis C Virus Cell Attachment and Infection.Hepatitis C virus infection upregulates CD55 expression on the hepatocyte surface and promotes association with virus particles.Attachment and Postattachment Receptors Important for Hepatitis C Virus Infection and Cell-to-Cell Transmission.A Point Mutation in the N-Terminal Amphipathic Helix α0 in NS3 Promotes Hepatitis C Virus Assembly by Altering Core Localization to the Endoplasmic Reticulum and Facilitating Virus Budding.Suppression of Host Innate Immune Response by Hepatitis C Virus via Induction of Autophagic Degradation of TRAF6.Enhancement of the Replication of Hepatitis C Virus Replicons of Genotypes 1 to 4 by Manipulation of CpG and UpA Dinucleotide Frequencies and Use of Cell Lines Expressing SECL14L2 for Antiviral Resistance Testing.Cooperation between the Hepatitis C Virus p7 and NS5B Proteins Enhances Virion Infectivity.Cell death-inducing DFFA-like effector b is required for hepatitis C virus entry into hepatocytes.Direct visualization of hepatitis C virus-infected Huh7.5 cells with a high titre of infectious chimeric JFH1-EGFP reporter virus in three-dimensional Matrigel cell cultures.Apolipoprotein E mediates attachment of clinical hepatitis C virus to hepatocytes by binding to cell surface heparan sulfate proteoglycan receptorsResponse of hepatitis C virus to long-term passage in the presence of alpha interferon: multiple mutations and a common phenotype.Syndecan-1 serves as the major receptor for attachment of hepatitis C virus to the surfaces of hepatocytes.Hepatitis C Virus Induces the Localization of Lipid Rafts to Autophagosomes for Its RNA Replication.The Serum Very-Low-Density Lipoprotein Serves as a Restriction Factor against Hepatitis C Virus Infection.HCV-induced autophagosomes are generated via homotypic fusion of phagophores that mediate HCV RNA replication.Construction of a chimeric hepatitis C virus replicon based on a strain isolated from a chronic hepatitis C patient.Cell culture-adaptive mutations in hepatitis C virus promote viral production by enhancing viral replication and release.
P2860
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P2860
Cell culture-adaptive mutations promote viral protein-protein interactions and morphogenesis of infectious hepatitis C virus
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Cell culture-adaptive mutation ...... f infectious hepatitis C virus
@ast
Cell culture-adaptive mutation ...... f infectious hepatitis C virus
@en
type
label
Cell culture-adaptive mutation ...... f infectious hepatitis C virus
@ast
Cell culture-adaptive mutation ...... f infectious hepatitis C virus
@en
prefLabel
Cell culture-adaptive mutation ...... f infectious hepatitis C virus
@ast
Cell culture-adaptive mutation ...... f infectious hepatitis C virus
@en
P2860
P356
P1433
P1476
Cell culture-adaptive mutation ...... f infectious hepatitis C virus
@en
P2093
Guangxiang Luo
Jieyun Jiang
P2860
P304
P356
10.1128/JVI.00004-12
P407
P577
2012-06-06T00:00:00Z