Toward a structural understanding of Clostridium difficile toxins A and B.
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Clostridium difficile Toxins A and B: Insights into Pathogenic Properties and Extraintestinal EffectsReactive Oxygen Species as Additional Determinants for Cytotoxicity of Clostridium difficile Toxins A and BAn Update on Clostridium difficile ToxinotypingWSES guidelines for management of Clostridium difficile infection in surgical patientsStructural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficileMechanism of Action and Epitopes of Clostridium difficile Toxin B-neutralizing Antibody Bezlotoxumab Revealed by X-ray CrystallographyBiochemical and Immunological Characterization of Truncated Fragments of the Receptor-Binding Domains of C. difficile Toxin A[Clostridium difficile infections in geriatric patients].Glucosylation Drives the Innate Inflammatory Response to Clostridium difficile Toxin AFrizzled proteins are colonic epithelial receptors for C. difficile toxin B.The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection.Bile acid recognition by the Clostridium difficile germinant receptor, CspC, is important for establishing infection.Toxin-mediated paracellular transport of antitoxin antibodies facilitates protection against Clostridium difficile infection.Infectious causes of necrotizing enterocolitis.Role of the intestinal microbiota in resistance to colonization by Clostridium difficile.Broad coverage of genetically diverse strains of Clostridium difficile by actoxumab and bezlotoxumab predicted by in vitro neutralization and epitope modeling.SpoIIID-mediated regulation of σK function during Clostridium difficile sporulation.Masking autoprocessing of Clostridium difficile toxin A by the C-terminus combined repetitive oligo peptides.Therapeutic manipulation of the microbiota: past, present, and considerations for the future.A chimeric protein comprising the glucosyltransferase and cysteine proteinase domains of toxin B and the receptor binding domain of toxin A induces protective immunity against Clostridium difficile infection in mice and hamsters.A genetic switch controls the production of flagella and toxins in Clostridium difficileDiagnosis of Clostridium difficile infection: an ongoing conundrum for clinicians and for clinical laboratories.Homogeneous and digital proximity ligation assays for the detection of Clostridium difficile toxins A and B.Immune-based treatment and prevention of Clostridium difficile infection.Pathogenesis of Clostridium difficile Infection and Its Potential Role in Inflammatory Bowel Disease.Phase Variation of Clostridium difficile Virulence Factors.Novel therapeutic strategies for Clostridium difficile infections.Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB.Enteric glial cells are susceptible to Clostridium difficile toxin B.Recombinant Mucin-Type Fusion Proteins with a Galα1,3Gal Substitution as Clostridium difficile Toxin A Inhibitors.Binding and entry of Clostridium difficile toxin B is mediated by multiple domains.Small Molecules That Sabotage Bacterial Virulence.Old and new models for studying host-microbe interactions in health and disease: C. difficile as an example.Clostridium difficile toxins A and B: Receptors, pores, and translocation into cells.Disease Progression and Resolution in Rodent Models of Clostridium difficile Infection and Impact of Antitoxin Antibodies and Vancomycin.Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface.Design and Purification of Subunit Vaccines for Prevention of Clostridium difficile Infection.Sensitive assays enable detection of serum IgG antibodies against Clostridium difficile toxin A and toxin B in healthy subjects and patients with Clostridium difficile infection.A small-molecule antivirulence agent for treating Clostridium difficile infection.Clostridium difficile the hospital plague.
P2860
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P2860
Toward a structural understanding of Clostridium difficile toxins A and B.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Toward a structural understanding of Clostridium difficile toxins A and B.
@ast
Toward a structural understanding of Clostridium difficile toxins A and B.
@en
type
label
Toward a structural understanding of Clostridium difficile toxins A and B.
@ast
Toward a structural understanding of Clostridium difficile toxins A and B.
@en
prefLabel
Toward a structural understanding of Clostridium difficile toxins A and B.
@ast
Toward a structural understanding of Clostridium difficile toxins A and B.
@en
P2860
P356
P1476
Toward a structural understanding of Clostridium difficile toxins A and B.
@en
P2093
D Borden Lacy
Rory N Pruitt
P2860
P356
10.3389/FCIMB.2012.00028
P577
2012-03-16T00:00:00Z