Pank1 deletion in leptin-deficient mice reduces hyperglycaemia and hyperinsulinaemia and modifies global metabolism without affecting insulin resistance
about
Induction of Neuron-Specific Degradation of Coenzyme A Models Pantothenate Kinase-Associated Neurodegeneration by Reducing Motor Coordination in MiceA high-throughput screen reveals new small-molecule activators and inhibitors of pantothenate kinases.Deregulated coenzyme A, loss of metabolic flexibility and diabetes.Excess coenzyme A reduces skeletal muscle performance and strength in mice overexpressing human PANK2.Allosteric Regulation of Mammalian Pantothenate Kinase.Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform.A therapeutic approach to pantothenate kinase associated neurodegeneration
P2860
Q27304502-30D17AC4-1589-4357-B860-AACE41C5E3B6Q35539926-ACE184DE-CC93-4FA5-AC9E-81B28CB77DB7Q37108651-5DB16325-073A-4C67-9325-4A468AC5F135Q38965702-B3911F5C-90EE-4A6D-AD47-801C7DB34F8FQ40565067-CB1C46BA-6C4B-4F67-B963-6F292A7AA96DQ49597537-66580A17-390F-4190-96D8-4A0F6C2C825CQ57798886-98D2B9D4-6887-4E5B-97F1-CF6C29B47326
P2860
Pank1 deletion in leptin-deficient mice reduces hyperglycaemia and hyperinsulinaemia and modifies global metabolism without affecting insulin resistance
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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name
Pank1 deletion in leptin-defic ...... t affecting insulin resistance
@ast
Pank1 deletion in leptin-defic ...... t affecting insulin resistance
@en
type
label
Pank1 deletion in leptin-defic ...... t affecting insulin resistance
@ast
Pank1 deletion in leptin-defic ...... t affecting insulin resistance
@en
prefLabel
Pank1 deletion in leptin-defic ...... t affecting insulin resistance
@ast
Pank1 deletion in leptin-defic ...... t affecting insulin resistance
@en
P2860
P1433
P1476
Pank1 deletion in leptin-defic ...... t affecting insulin resistance
@en
P2093
Charles O Rock
Roberta Leonardi
P2860
P2888
P304
P356
10.1007/S00125-014-3245-5
P577
2014-04-30T00:00:00Z