High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.
about
Wide-ranging and unexpected consequences of altered Pol II catalytic activity in vivo.Trigger loop of RNA polymerase is a positional, not acid-base, catalyst for both transcription and proofreading.Kinetics of nucleotide entry into RNA polymerase active site provides mechanism for efficiency and fidelity.Correction: High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.The architecture of an empirical genotype-phenotype map.RNA-mediated gene regulation is less evolvable than transcriptional regulation.
P2860
High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.
@ast
High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.
@en
type
label
High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.
@ast
High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.
@en
prefLabel
High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.
@ast
High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.
@en
P2093
P2860
P50
P1433
P1476
High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop
@en
P2093
Craig D Kaplan
Huiyan Jin
Jan Van den Brulle
Jui M Dave
Kenny C Lam
Leung K Tang
Nandhini Muthukrishnan
Olivia C Erinne
Ralf Strohner
P2860
P304
P356
10.1371/JOURNAL.PGEN.1006321
P577
2016-11-29T00:00:00Z