Elucidating the early stages of keratin filament assembly
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The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitroA human keratin 14 "knockout": the absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament proteinKeratin 16 and keratin 17 mutations cause pachyonychia congenitaA dysfunctional desmin mutation in a patient with severe generalized myopathyGenetic mutations in the K1 and K10 genes of patients with epidermolytic hyperkeratosis. Correlation between location and disease severityMaking a connection: direct binding between keratin intermediate filaments and desmosomal proteinsOverexpression of the human NFM subunit in transgenic mice modifies the level of endogenous NFL and the phosphorylation state of NFH subunitsThe 47-kD lens-specific protein phakinin is a tailless intermediate filament protein and an assembly partner of filensinOnset of re-epithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: defining a potential role for keratin 16Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skinIsolation and chromosomal localization of a cornea-specific human keratin 12 gene and detection of four mutations in Meesmann corneal epithelial dystrophyStructural basis for heteromeric assembly and perinuclear organization of keratin filamentsLocalization of the Kar3 kinesin heavy chain-related protein requires the Cik1 interacting protein.In Vitro Model of the Epidermis: Connecting Protein Function to 3D StructureCytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodiesHow Egg Case Proteins Can Protect Cuttlefish Offspring?A procedure for refining a coiled coil protein structure using x-ray fiber diffraction and modeling.Effects of sulfur mustard on the basal cell adhesion complex.Polycystin-1 interacts with intermediate filaments.Directed expression of a chimeric type II keratin partially rescues keratin 5-null mice.Defining the properties of the nonhelical tail domain in type II keratin 5: insight from a bullous disease-causing mutationPairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filamentsSorting out IF networks: consequences of domain swapping on IF recognition and assembly.Keratin 9 gene mutations in epidermolytic palmoplantar keratoderma (EPPK).A missense mutation in the rod domain of keratin 14 associated with recessive epidermolysis bullosa simplex.The importance of intramolecular ion pairing in intermediate filamentsSelf-consistent field theory for the interactions between keratin intermediate filaments.Self-organization of keratin intermediate filaments into cross-linked networksInteraction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus.Properties of intermediate filament networks assembled from keratin 8 and 18 in the presence of Mg²+Deletions in epidermal keratins leading to alterations in filament organization in vivo and in intermediate filament assembly in vitroDisease severity correlates with position of keratin point mutations in patients with epidermolysis bullosa simplex.Dynamics of keratin assembly: exogenous type I keratin rapidly associates with type II keratin in vivo.The roles of the rod end and the tail in vimentin IF assembly and IF network formation.Expression of an epidermal keratin protein in liver of transgenic mice causes structural and functional abnormalities.A nontetrameric species is the major soluble form of keratin in Xenopus oocytes and rabbit reticulocyte lysates.Functional differences between keratins of stratified and simple epithelia.A small surface hydrophobic stripe in the coiled-coil domain of type I keratins mediates tetramer stability.Expression of chicken lamin B2 in Escherichia coli: characterization of its structure, assembly, and molecular interactionsKeratin incorporation into intermediate filament networks is a rapid process.
P2860
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P2860
Elucidating the early stages of keratin filament assembly
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Elucidating the early stages of keratin filament assembly
@ast
Elucidating the early stages of keratin filament assembly
@en
type
label
Elucidating the early stages of keratin filament assembly
@ast
Elucidating the early stages of keratin filament assembly
@en
prefLabel
Elucidating the early stages of keratin filament assembly
@ast
Elucidating the early stages of keratin filament assembly
@en
P2860
P356
P1476
Elucidating the early stages of keratin filament assembly
@en
P2093
P2860
P304
P356
10.1083/JCB.111.1.153
P407
P577
1990-07-01T00:00:00Z