Pattern of mutation in the genome of influenza A virus on adaptation to increased virulence in the mouse lung: identification of functional themes.
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Animal models of respiratory syncytial virus infection and diseaseEvidence for a Novel Mechanism of Influenza Virus-Induced Type I Interferon Expression by a Defective RNA-Encoded ProteinHighly Conserved Protective Epitopes on Influenza B VirusesMechanism-based covalent neuraminidase inhibitors with broad-spectrum influenza antiviral activityAirborne transmission of highly pathogenic H7N1 influenza virus in ferretsInfluenza A virus transmission via respiratory aerosols or droplets as it relates to pandemic potentialParallel genotypic adaptation: when evolution repeats itselfCharacterization of the 1918 "Spanish" influenza virus matrix gene segmentA novel activation mechanism of avian influenza virus H9N2 by furin.Molecular determinants of influenza virus pathogenesis in mice.Hemagglutinin 222D/G polymorphism facilitates fast intra-host evolution of pandemic (H1N1) 2009 influenza A viruses.Mammalian adaptive mutations of the PA protein of highly pathogenic avian H5N1 influenza virus.Evolutionary and transmission dynamics of reassortant H5N1 influenza virus in Indonesia.Characterization of H5N1 influenza virus variants with hemagglutinin mutations isolated from patientsMouse lung-adapted mutation of E190G in hemagglutinin from H5N1 influenza virus contributes to attenuation in mice.Molecular characterization of mammalian-adapted Korean-type avian H9N2 virus and evaluation of its virulence in mice.Virulence of a novel reassortant canine H3N2 influenza virus in ferret, dog and mouse models.Inefficient control of host gene expression by the 2009 pandemic H1N1 influenza A virus NS1 proteinAdaptation of pandemic H1N1 influenza viruses in mice.PB2 residue 158 is a pathogenic determinant of pandemic H1N1 and H5 influenza a viruses in mice.Rapid acquisition of polymorphic virulence markers during adaptation of highly pathogenic avian influenza H5N8 virus in the mouseMutations in PA, NP, and HA of a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to miceSwine-origin influenza-virus-induced acute lung injury: Novel or classical pathogenesis?A comparative study of short linear motif compositions of the influenza A virus ribonucleoproteinsAnticipated and current preventive behaviors in response to an anticipated human-to-human H5N1 epidemic in the Hong Kong Chinese general population.Nuclear factor 90 negatively regulates influenza virus replication by interacting with viral nucleoprotein.Standing genetic variation in contingency loci drives the rapid adaptation of Campylobacter jejuni to a novel host.Genomic and protein structural maps of adaptive evolution of human influenza A virus to increased virulence in the mouse.Molecular basis of replication of duck H5N1 influenza viruses in a mammalian mouse model.Low-pathogenic avian influenza virus A/turkey/Ontario/6213/1966 (H5N1) is the progenitor of highly pathogenic A/turkey/Ontario/7732/1966 (H5N9).Multifunctional adaptive NS1 mutations are selected upon human influenza virus evolution in the mouse.PB2 and hemagglutinin mutations are major determinants of host range and virulence in mouse-adapted influenza A virusCoronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus.Differential microRNA expression following infection with a mouse-adapted, highly virulent avian H5N2 virus.Mouse-adapted H9N2 influenza A virus PB2 protein M147L and E627K mutations are critical for high virulence.The evolutionary pattern of glycosylation sites in influenza virus (H5N1) hemagglutinin and neuraminidase.Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulence.Characterization of an H10N8 influenza virus isolated from Dongting lake wetland.A combination of HA and PA mutations enhances virulence in a mouse-adapted H6N6 influenza A virus.Mutations in influenza virus M1 CCHH, the putative zinc finger motif, cause attenuation in mice and protect mice against lethal influenza virus infection.
P2860
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P2860
Pattern of mutation in the genome of influenza A virus on adaptation to increased virulence in the mouse lung: identification of functional themes.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Pattern of mutation in the gen ...... fication of functional themes.
@ast
Pattern of mutation in the gen ...... fication of functional themes.
@en
type
label
Pattern of mutation in the gen ...... fication of functional themes.
@ast
Pattern of mutation in the gen ...... fication of functional themes.
@en
prefLabel
Pattern of mutation in the gen ...... fication of functional themes.
@ast
Pattern of mutation in the gen ...... fication of functional themes.
@en
P2093
P2860
P356
P1476
Pattern of mutation in the gen ...... fication of functional themes.
@en
P2093
P2860
P304
P356
10.1073/PNAS.111165798
P407
P577
2001-05-22T00:00:00Z