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Detection of direct binding of human herpesvirus 8-encoded interleukin-6 (vIL-6) to both gp130 and IL-6 receptor (IL-6R) and identification of amino acid residues of vIL-6 important for IL-6R-dependent and -independent signalingSolution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complexInterleukin-6-type cytokine signalling through the gp130/Jak/STAT pathwayCrystal structure of a cytokine-binding region of gp130.Interleukin-6- and cyclic AMP-mediated signaling potentiates neuroendocrine differentiation of LNCaP prostate tumor cells.Host defences against Giardia lambliaThe signal transducer gp130: Solution structure of the carboxy-terminal domain of the cytokine receptor homology regionStructure of the extracellular domains of the human interleukin-6 receptor alpha -chainCrystal Structure of Interleukin-6 in Complex with a Modified Nucleic Acid LigandThe N-terminal cytokine binding domain of LIFR is required for CNTF binding and signalingIdentification of three distinct receptor binding sites of murine interleukin-11Interleukin-11 signals through the formation of a hexameric receptor complexNeutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6Membrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitroReceptor recognition sites of cytokines are organized as exchangeable modules. Transfer of the leukemia inhibitory factor receptor-binding site from ciliary neurotrophic factor to interleukin-6.Affinity maturation of leukemia inhibitory factor and conversion to potent antagonists of signaling.Matrix-assisted refolding and purification of placenta-derived recombinant human interleukin-6 produced in Escherichia coli.The SCHOOL of nature: I. Transmembrane signaling.A ligand peptide motif selected from a cancer patient is a receptor-interacting site within human interleukin-11.Amyotrophic lateral sclerosis, gene deregulation in the anterior horn of the spinal cord and frontal cortex area 8: implications in frontotemporal lobar degenerationHuman herpesvirus 8 interleukin-6 (vIL-6) signals through gp130 but has structural and receptor-binding properties distinct from those of human IL-6.The Therapeutic Potential of Anti-Inflammatory Exerkines in the Treatment of AtherosclerosisMeasuring IL-6 and sIL-6R in serum from patients treated with tocilizumab and/or siltuximab following CAR T cell therapy.A high-affinity protein binder that blocks the IL-6/STAT3 signaling pathway effectively suppresses non-small cell lung cancer.Receptor recognition by gp130 cytokines.Signaling through a novel domain of gp130 mediates cell proliferation and activation of Hck and Erk kinases.Glucocorticoids potentiate IL-6-induced SP-B expression in H441 cells by enhancing the JAK-STAT signaling pathway.High-level transient expression of ER-targeted human interleukin 6 in Nicotiana benthamianaMicrovasculature in gingivitis and chronic periodontitis: disruption of vascular networks with protracted inflammation.Recombinant production of human interleukin 6 in Escherichia coliForced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells.Andrographolide, an herbal medicine, inhibits interleukin-6 expression and suppresses prostate cancer cell growth.Influence of interleukin-6 and G174C polymorphism in IL-6 gene on obesity and energy balance.The cytokine receptor gp130: faithfully promiscuous.Role of monocytes in atherogenesis.Serum levels of interleukin-6 type cytokines and soluble interleukin-6 receptor in patients with rheumatoid arthritis.Neutralizing Anti-IL20 Antibody Treatment Significantly Modulates Low Grade Inflammation without Affecting HbA1c in Type 2 Diabetic db/db MiceSerum interleukin-6 level as an early marker of injury severity in trauma patients in an urban low-income setting: a cross-sectional study.Interleukin-6: the missing element of the neurocognitive deterioration in schizophrenia? The focus on genetic underpinnings, cognitive impairment and clinical manifestation.In vitro and in vivo antitumor effects of the recombinant immunotoxin IL6(T23)-PE38KDEL in multiple myeloma
P2860
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P2860
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Interleukin-6: structure-function relationships.
@ast
Interleukin-6: structure-function relationships.
@en
type
label
Interleukin-6: structure-function relationships.
@ast
Interleukin-6: structure-function relationships.
@en
prefLabel
Interleukin-6: structure-function relationships.
@ast
Interleukin-6: structure-function relationships.
@en
P2093
P2860
P356
P1433
P1476
Interleukin-6: structure-function relationships
@en
P2093
P2860
P304
P356
10.1002/PRO.5560060501
P577
1997-05-01T00:00:00Z