Activation of the genetically defined m1 muscarinic receptor potentiates N-methyl-D-aspartate (NMDA) receptor currents in hippocampal pyramidal cells.
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Memory trace replay: the shaping of memory consolidation by neuromodulationA CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2Differential effects of PACAP-38 on synaptic responses in rat hippocampal CA1 regionScopolamine administration modulates muscarinic, nicotinic and NMDA receptor systemsThe antipsychotic potential of muscarinic allosteric modulationAllosteric modulation of the M1 muscarinic acetylcholine receptor: improving cognition and a potential treatment for schizophrenia and Alzheimer's diseaseAllosteric activators of muscarinic receptors as novel approaches for treatment of CNS disorders.Selective activation of M4 muscarinic acetylcholine receptors reverses MK-801-induced behavioral impairments and enhances associative learning in rodents.Differential effects of m1 and m2 receptor antagonists in perirhinal cortex on visual recognition memory in monkeys.M-type potassium channels modulate Schaffer collateral-CA1 glutamatergic synaptic transmission.Muscarinic and nicotinic acetylcholine receptor agonists and allosteric modulators for the treatment of schizophreniaTargeting glutamate synapses in schizophreniaBeyond the dopamine receptor: novel therapeutic targets for treating schizophrenia.Discovery and characterization of novel subtype-selective allosteric agonists for the investigation of M(1) receptor function in the central nervous system.A comparison of scopolamine and biperiden as a rodent model for cholinergic cognitive impairmentA novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learningSelective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation.Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model.Antipsychotic drug action: targets for drug discovery with neurochemical imaging.M1 muscarinic receptors boost synaptic potentials and calcium influx in dendritic spines by inhibiting postsynaptic SK channels.Cortical M1 receptor concentration increases without a concomitant change in function in Alzheimer's disease.The NMDA Receptor and Schizophrenia: From Pathophysiology to Treatment.Regulation of synaptic plasticity in a schizophrenia model.Subunit-dependent modulation of kainate receptors by muscarinic acetylcholine receptorsNicotinic and muscarinic agonists and acetylcholinesterase inhibitors stimulate a common pathway to enhance GluN2B-NMDAR responses.Inhibition of post-synaptic Kv7/KCNQ/M channels facilitates long-term potentiation in the hippocampusRole of the cholinergic muscarinic system in bipolar disorder and related mechanism of action of antipsychotic agents.Pro-cognitive and antipsychotic efficacy of the alpha7 nicotinic partial agonist SSR180711 in pharmacological and neurodevelopmental latent inhibition models of schizophrenia.An acetylcholinesterase inhibitor, eserine, induces long-term depression at CA3-CA1 synapses in the hippocampus of adult ratsNeuromodulatory neurotransmitters influence LTP-like plasticity in human cortex: a pharmaco-TMS study.Discovery and SAR of muscarinic receptor subtype 1 (M1) allosteric activators from a molecular libraries high throughput screen. Part 1: 2,5-dibenzyl-2H-pyrazolo[4,3-c]quinolin-3(5H)-ones as positive allosteric modulators.5-Hydroxytryptamine 5HT2C receptors form a protein complex with N-methyl-D-aspartate GluN2A subunits and activate phosphorylation of Src protein to modulate motoneuronal depolarization.Src in synaptic transmission and plasticity.Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal modelsMuscarinic cholinergic receptor M1 in the rat basolateral amygdala: ultrastructural localization and synaptic relationships to cholinergic axons.Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus.Neurotransmitter receptor expression and activity during neuronal differentiation of embryonal carcinoma and stem cells: from basic research towards clinical applications.Role for the M1 Muscarinic Acetylcholine Receptor in Top-Down Cognitive Processing Using a Touchscreen Visual Discrimination Task in MiceLayer 2/3 synapses in monocular and binocular regions of tree shrew visual cortex express mAChR-dependent long-term depression and long-term potentiation.Inactivation of JAK2/STAT3 signaling axis and downregulation of M1 mAChR cause cognitive impairment in klotho mutant mice, a genetic model of aging
P2860
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P2860
Activation of the genetically defined m1 muscarinic receptor potentiates N-methyl-D-aspartate (NMDA) receptor currents in hippocampal pyramidal cells.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Activation of the genetically ...... n hippocampal pyramidal cells.
@ast
Activation of the genetically ...... n hippocampal pyramidal cells.
@en
type
label
Activation of the genetically ...... n hippocampal pyramidal cells.
@ast
Activation of the genetically ...... n hippocampal pyramidal cells.
@en
prefLabel
Activation of the genetically ...... n hippocampal pyramidal cells.
@ast
Activation of the genetically ...... n hippocampal pyramidal cells.
@en
P2093
P2860
P356
P1476
Activation of the genetically ...... n hippocampal pyramidal cells.
@en
P2093
P2860
P304
11465-11470
P356
10.1073/PNAS.95.19.11465
P407
P577
1998-09-01T00:00:00Z