Defective Rac-mediated proliferation and survival after targeted mutation of the beta1 integrin cytodomain.
about
Nuclear translocation of integrin cytoplasmic domain-associated protein 1 stimulates cellular proliferation.Integrin-α5 coordinates assembly of posterior cranial placodes in zebrafish and enhances Fgf-dependent regulation of otic/epibranchial cells.FHL3 is an actin-binding protein that regulates alpha-actinin-mediated actin bundling: FHL3 localizes to actin stress fibers and enhances cell spreading and stress fiber disassemblyPINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytesBeta1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelinationPhosphoinositide 3-kinase p85beta regulates invadopodium formation.Trop-2 promotes prostate cancer metastasis by modulating β(1) integrin functions.Integrins in development and cancer.Genetic interaction between integrins and moleskin, a gene encoding a Drosophila homolog of importin-7.Analysis of conserved residues in the betapat-3 cytoplasmic tail reveals important functions of integrin in multiple tissues.Cell adhesion molecule regulation of nucleocytoplasmic trafficking.Contributions of the integrin β1 tail to cell adhesive forces.Integrins regulate microtubule nucleating activity of centrosome through mitogen-activated protein kinase/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase (MEK/ERK) signaling.Nuclear localization of the ERK MAP kinase mediated by Drosophila alphaPS2betaPS integrin and importin-7.Specific β-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells.The MAPK MEK1/2-ERK1/2 Pathway and Its Implication in Hepatocyte Cell Cycle Control.The extracellular matrix as an adhesion checkpoint for mammary epithelial function.Joint requirement for Rac and ERK activities underlies the mid-G1 phase induction of cyclin D1 and S phase entry in both epithelial and mesenchymal cellsSynergistic control of cell adhesion by integrins and syndecans.Integrins in lens development and disease.Integrins and cell-fate determination.Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the β1 integrin-RACK1 axisEffects of rho kinase and actin stress fibers on sustained extracellular signal-regulated kinase activity and activation of G(1) phase cyclin-dependent kinases.Down-regulation of BRCA2 expression by collagen type I promotes prostate cancer cell proliferation.Focal contact clustering in osteoblastic cells under mechanical stresses: microgravity and cyclic deformation.Inhibition of Rac GTPase triggers a c-Jun- and Bim-dependent mitochondrial apoptotic cascade in cerebellar granule neurons.Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells.Targeted deletion of the integrin beta4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-kappaB, causing defects in epidermal growth and migrationThe absence of caveolin-1 increases proliferation and anchorage- independent growth by a Rac-dependent, Erk-independent mechanism.Synthetic molecules that protect cells from anoikis and their use in cell transplantation.EGF-induced ERK-activation downstream of FAK requires rac1-NADPH oxidase.β1 integrin-dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin.Integrin α2 marks a niche of trophoblast progenitor cells in first trimester human placenta.FAK regulates Cdk2 in EGF-stimulated primary cultures of hepatocytes.
P2860
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P2860
Defective Rac-mediated proliferation and survival after targeted mutation of the beta1 integrin cytodomain.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Defective Rac-mediated prolife ...... the beta1 integrin cytodomain.
@ast
Defective Rac-mediated prolife ...... the beta1 integrin cytodomain.
@en
type
label
Defective Rac-mediated prolife ...... the beta1 integrin cytodomain.
@ast
Defective Rac-mediated prolife ...... the beta1 integrin cytodomain.
@en
prefLabel
Defective Rac-mediated prolife ...... the beta1 integrin cytodomain.
@ast
Defective Rac-mediated prolife ...... the beta1 integrin cytodomain.
@en
P2093
P2860
P50
P356
P1476
Defective Rac-mediated prolife ...... the beta1 integrin cytodomain.
@en
P2093
Filippo G Giancotti
Fiorella Altruda
John M Kyriakis
Laura Barberis
Lorenzo Silengo
Mara Brancaccio
Ornella Azzolino
P2860
P304
P356
10.1083/JCB.200111065
P407
P577
2002-04-29T00:00:00Z