Molecular events initiating exit of a copper-transporting ATPase ATP7B from the trans-Golgi network
about
A fresh view of the cell biology of copper in enterobacteria.Interactions between metal-binding domains modulate intracellular targeting of Cu(I)-ATPase ATP7B, as revealed by nanobody binding.Communication between the N and C termini is required for copper-stimulated Ser/Thr phosphorylation of Cu(I)-ATPase (ATP7B).Neuronal differentiation is associated with a redox-regulated increase of copper flow to the secretory pathway.Biometals in rare neurodegenerative disorders of childhood.Disease-causing point-mutations in metal-binding domains of Wilson disease protein decrease stability and increase structural dynamics.Distinct phenotype of a Wilson disease mutation reveals a novel trafficking determinant in the copper transporter ATP7B.Golgi in copper homeostasis: a view from the membrane trafficking field.Copper trafficking to the secretory pathway.Unresolved questions in human copper pump mechanisms.Dynamics of the metal binding domains and regulation of the human copper transporters ATP7B and ATP7A.Enthalpy-entropy compensation at play in human copper ion transfer.Wilson disease protein ATP7B utilizes lysosomal exocytosis to maintain copper homeostasis.The six metal binding domains in human copper transporter, ATP7B: molecular biophysics and disease-causing mutations.HUMAN COPPER TRANSPORTER ATP7B (WILSON DISEASE PROTEIN) FORMS STABLE DIMERS IN VITRO AND IN CELLS.The metal chaperone Atox1 regulates the activity of the human copper transporter ATP7B by modulating domain dynamics.Probing functional roles of Wilson disease protein (ATP7B) copper-binding domains in yeast.Effect of cisplatin on the transport activity of PII-type ATPases.
P2860
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P2860
Molecular events initiating exit of a copper-transporting ATPase ATP7B from the trans-Golgi network
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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name
Molecular events initiating ex ...... B from the trans-Golgi network
@ast
Molecular events initiating ex ...... B from the trans-Golgi network
@en
type
label
Molecular events initiating ex ...... B from the trans-Golgi network
@ast
Molecular events initiating ex ...... B from the trans-Golgi network
@en
prefLabel
Molecular events initiating ex ...... B from the trans-Golgi network
@ast
Molecular events initiating ex ...... B from the trans-Golgi network
@en
P2093
P2860
P356
P1476
Molecular events initiating ex ...... B from the trans-Golgi network
@en
P2093
Arnab Gupta
Corey H Yu
Elena Polishchuk
Nesrin M Hasan
Oleg Y Dmitriev
Roman Polishchuk
Svetlana Lutsenko
P2860
P304
36041-36050
P356
10.1074/JBC.M112.370403
P407
P577
2012-08-16T00:00:00Z