Mice whose B cells cannot produce the T15 idiotype also lack an antigen-specific helper T cell required for T15 expression.
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Influence of helper T cells on the expression of a murine intrastrain crossreactive idiotypeSelective suppression of the major idiotypic component of an antihapten response by soluble T cell-derived factors with idiotypic or anti-idiotypic receptors.Expression of an idiotype (Id-460) during in vivo anti-dinitrophenyl antibody responses. I. Mapping of genes for Id-460 expression to the variable region of immunoglobulin heavy-chain locus and to the variable region of immunoglobulin kappa-light-chAntigen-specific helper T cells required for dominant production of an idiotype (THId) are not under immune response (Ir) gene controlT cell regulation of IgG subclass antibody production in response to T-independent antigens.Generation of idiotype-specific T cell help through network perturbationAntigen-specific helper T cells required for dominant idiotype expression are not H-2 restricted.Balb/c T cells have the potential to recognize the TEPC 15 prototype antibody and its somatic variants.Alteration of clonal profile. III. T15 ontogenetic advantages are not sufficient for establishing idiotypic dominance in adoptive transferAnalysis of the response of B cells from CBA/N-defective mice to nonspecific T cell helpExpression of an idiotype (Id-460) during in vivo anti-dinitrophenyl antibody responses. II. Transient idiotypic dominance.Expression of an idiotype (Id-460) during in vivo anti-dinitrophenyl antibody responses. III. Detection of Id-460 in normal serum that does not bind dinitrophenyl.Mice with the xid defect have helper cells for T15 idiotype-dominant anti-phosphorylcholine primary and secondary plaque-forming cells responses.Regulatory idiotypes. T helper cells recognize a shared VH idiotope on phosphorylcholine-specific antibodiesAnti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae.Unbalanced X chromosome mosaicism in B cells of mice with X-linked immunodeficiencyRole of variable region gene expression and environmental selection in determining the antiphosphorylcholine B cell repertoireNon-dinitrophenyl-binding immunoglobulin that bears a dominant idiotype (Id460) associated with antidinitrophenyl antibody is specific for an antigen on Pasteurella pneumotropica.Idiotype-specific T lymphocytes. II. capability of generation of idiotype-specific T lymphocytes is determined by corresponding VH gene.Subpopulations of B cells distinguished by cell surface expression of Ia antigens. Correlation of Ia and idiotype during activation by cloned Ia-restricted T cellsIdiotype connectance in the immune system. II. A heavy chain variable region idiotope that dominates the antibody response to the p-azobenzenearsonate group is a minor idiotope in the response to trinitrophenyl group.Distinct functional phenotypes of cloned Ia-restricted helper T cells.The antibody response to specific immune complexes is under genetic control and correlates with the expression of a recurrent idiotype.Development of Ly-1+ B cells in immunodeficient CBA/N miceProspects for the treatment of B cell tumors using idiotypic vaccination.Modification of emerging repertoires by immunosuppression in immunodeficient mice results in autoimmunity.Isotype-specific T cell regulation of immunoglobulin expression.1984: all idiotypes are equal, but some are more equal than others.T-cell helper circuits.Cell surface antigen marking the stages of murine T cell ontogeny and its functional subsets.Selective effects of ionizing radiations on immunoregulatory cells.CBA/N immune defective mice; evidence for the failure of a B cell subpopulation to be expressed.The collaborative phenotype of secondary B cells is determined by T lymphocytes during in vivo immunization.Generation of helper T cells that recognize a cross-reactive idiotype through a network mechanism.T cell development in B cell-deficient mice. V. Stopping anti-mu treatment results in Igh-restricted expansion of the T suppressor cell repertoire concomitant with the development of normal immunoglobulin levelsCell-to-cell interaction controlled by immunoglobulin genes. Role of Thy-1-, Lyt-1+, Ig+ (B') cell in allotype-restricted antibody productionAnalysis of histocompatibility requirements for proliferative and helper T cell activity. T cell populations depleted of alloreactive cells by negative selection.Helper T cell recognition of the variable domains of a mouse myeloma protein (315). Effect of the major histocompatibility complex and domain conformation.Regulation of azophenylarsonate-specific repertoire expression. 1. Frequency of cross-reactive idiotype-positive B cells in A/J and BALB/c mice.The immune response to bacterial dextrans. VI. No correlation between the frequency of cells expressing a major anti-dextran idiotype and the idiotype profiles of specific antibody responses.
P2860
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P2860
Mice whose B cells cannot produce the T15 idiotype also lack an antigen-specific helper T cell required for T15 expression.
description
1979 nî lūn-bûn
@nan
1979年の論文
@ja
1979年学术文章
@wuu
1979年学术文章
@zh-cn
1979年学术文章
@zh-hans
1979年学术文章
@zh-my
1979年学术文章
@zh-sg
1979年學術文章
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1979年學術文章
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1979年學術文章
@zh-hant
name
Mice whose B cells cannot prod ...... l required for T15 expression.
@ast
Mice whose B cells cannot prod ...... l required for T15 expression.
@en
type
label
Mice whose B cells cannot prod ...... l required for T15 expression.
@ast
Mice whose B cells cannot prod ...... l required for T15 expression.
@en
prefLabel
Mice whose B cells cannot prod ...... l required for T15 expression.
@ast
Mice whose B cells cannot prod ...... l required for T15 expression.
@en
P2860
P356
P1476
Mice whose B cells cannot prod ...... l required for T15 expression.
@en
P2093
P2860
P304
P356
10.1084/JEM.150.6.1399
P407
P577
1979-12-01T00:00:00Z