Lysophosphatidylcholine and secretory phospholipase A2 in vascular disease: mediators of endothelial dysfunction and atherosclerosis.
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Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque developmentA-002 (Varespladib), a phospholipase A2 inhibitor, reduces atherosclerosis in guinea pigs.Elevated pro-inflammatory and lipotoxic mucosal lipids characterise irritable bowel syndrome.Prehypertension-associated elevation in circulating lysophosphatidlycholines, Lp-PLA2 activity, and oxidative stress.Comprehensive metabolomics identified lipid peroxidation as a prominent feature in human plasma of patients with coronary heart diseasesLyso-phosphatidylcholine induces osteogenic gene expression and phenotype in vascular smooth muscle cells.Implication of lipoprotein associated phospholipase A2 activity in oxLDL uptake by macrophages.Plasma metabolomics reveal alterations of sphingo- and glycerophospholipid levels in non-diabetic carriers of the transcription factor 7-like 2 polymorphism rs7903146Lysophosphatidylcholine triggers TLR2- and TLR4-mediated signaling pathways but counteracts LPS-induced NO synthesis in peritoneal macrophages by inhibiting NF-κB translocation and MAPK/ERK phosphorylation.The 763C>G Polymorphism of The Secretory PLA2IIa Gene Is Associated with Endometriosis in Iranian WomenA novel truncated form of apolipoprotein A-I transported by dense LDL is increased in diabetic patients.Metabolite and Lipid Profiling of Biobank Plasma Samples Collected Prior to Onset of Rheumatoid Arthritis.Product inhibition of secreted phospholipase A2 may explain lysophosphatidylcholines' unexpected therapeutic propertiesIntegration of cytokine biology and lipid metabolism in strokeAssociation of age-related changes in circulating intermediary lipid metabolites, inflammatory and oxidative stress markers, and arterial stiffness in middle-aged men.Altered lipid metabolism in brain injury and disorders.Effect of probiotic Lactobacillus rhamnosus GG intervention on global serum lipidomic profiles in healthy adults.G2A and LPC: regulatory functions in immunity.Identification of lysophosphatidylcholine-chlorohydrin in human atherosclerotic lesions.Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain.Differences between serum polar lipid profiles of male and female rheumatoid arthritis patients in response to glucocorticoid treatment.Global Metabolic Profiling of Plasma Shows that Three-Year Mild-Caloric Restriction Lessens an Age-Related Increase in Sphingomyelin and Reduces L-leucine and L-phenylalanine in Overweight and Obese Subjects.TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells.Baseline elevated Lp-PLA2 is associated with increased risk for re-stenosis after stent placement.Recent developments with lipoprotein-associated phospholipase A2 inhibitors.Effect of lyso-phosphatidylcholine and Schnurri-3 on osteogenic transdifferentiation of vascular smooth muscle cells to calcifying vascular cells in 3D culture.Agonist potency at P2X7 receptors is modulated by structurally diverse lipids.Blood Metabolic Signatures of Body Mass Index: A Targeted Metabolomics Study in the EPIC Cohort.Deletion of the G2A receptor fails to attenuate experimental autoimmune encephalomyelitis.A metabolomic investigation of the effects of vitamin E supplementation in humans.GPR119 is essential for oleoylethanolamide-induced glucagon-like peptide-1 secretion from the intestinal enteroendocrine L-cell.Lysophosphatidylcholine induces cytotoxicity/apoptosis and IL-8 production of human endothelial cells: Related mechanisms.
P2860
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P2860
Lysophosphatidylcholine and secretory phospholipase A2 in vascular disease: mediators of endothelial dysfunction and atherosclerosis.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Lysophosphatidylcholine and se ...... sfunction and atherosclerosis.
@ast
Lysophosphatidylcholine and se ...... sfunction and atherosclerosis.
@en
type
label
Lysophosphatidylcholine and se ...... sfunction and atherosclerosis.
@ast
Lysophosphatidylcholine and se ...... sfunction and atherosclerosis.
@en
prefLabel
Lysophosphatidylcholine and se ...... sfunction and atherosclerosis.
@ast
Lysophosphatidylcholine and se ...... sfunction and atherosclerosis.
@en
P2093
P1476
Lysophosphatidylcholine and se ...... sfunction and atherosclerosis.
@en
P2093
Alan B Lumsden
Changyi Chen
Panagiotis Kougias
Peter H Lin
P304
P577
2005-12-19T00:00:00Z