RAP80 is critical in maintaining genomic stability and suppressing tumor development. - Test2 - elhamkhani - TriplyDB

RAP80 is critical in maintaining genomic stability and suppressing tumor development.

RAP80 is critical in maintaining genomic stability and suppressing tumor development.

http://www.wikidata.org/entity/Q36352398

about

Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombination Fine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at work Molecular Basis for Impaired DNA Damage Response Function Associated with the RAP80 E81 Defect PALB2: the hub of a network of tumor suppressors involved in DNA damage responses PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair.Structural and functional implication of RAP80 ΔGlu81 mutation.Deciphering the BRCA1 Tumor Suppressor Network.MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links.BRE plays an essential role in preventing replicative and DNA damage-induced premature senescence.RAP80 regulates epithelial-mesenchymal transition related with metastasis and malignancy of cancer.53BP1, BRCA1, and the choice between recombination and end joining at DNA double-strand breaks.RNA splicing: a new player in the DNA damage response Factors forming the BRCA1-A complex orchestrate BRCA1 recruitment to the sites of DNA damage.Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding.RAP80 is an independent prognosis biomarker for the outcome of patients with esophageal squamous cell carcinoma.

P2860

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P2860

RAP80 is critical in maintaining genomic stability and suppressing tumor development.

http://www.wikidata.org/entity/Q36352398

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

RAP80 is critical in maintaining genomic stability and suppressing tumor development.

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RAP80 is critical in maintaining genomic stability and suppressing tumor development.

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type

label

RAP80 is critical in maintaining genomic stability and suppressing tumor development.

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RAP80 is critical in maintaining genomic stability and suppressing tumor development.

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prefLabel

RAP80 is critical in maintaining genomic stability and suppressing tumor development.

@ast

RAP80 is critical in maintaining genomic stability and suppressing tumor development.

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0008-5472.CAN-12-1484

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Cancer Research

P1476

RAP80 is critical in maintaining genomic stability and suppressing tumor development.

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P2093

Anton M Jetten

http://www.w3.org/2001/XMLSchema#string

Daniel Menendez

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John E French

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Kyathanahalli S Janardhan

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Michael A Resnick

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Zhengyu Yin

http://www.w3.org/2001/XMLSchema#string

P2860

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response

The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks

CCDC98 targets BRCA1 to DNA damage sites

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

The first 30 years of p53: growing ever more complex

The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

Cell-cycle checkpoints and cancer

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5080-5090

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scholarly article

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10.1158/0008-5472.CAN-12-1484

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19

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22896338

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3482830

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